Abstract
Purpose: :
To evaluate the ocular perfusion pressure in patients during hemodialysis session.
Methods: :
A prospective, observational case series was developed. IOP was evaluated using Tonopen tonometer. Systolic and diastolic blood pressure were also measured with manual sphygmomanometer. 67 eyes of 35 patients were evaluated in 3 different times during hemodialysis session. The ocular perfusion pressure was estimated by the difference between 2/3 of the medium blood pressure and intra ocular pressure. Generalized estimating equations was performed to evaluate the difference of the repeated measures with the apropriate correction for inter-eye dependency.
Results: :
There was no statistically significant difference in ocular perfusion pressure among the three measurements (p=0.998). It was also observed no difference for IOP (p=0.605) and diastolic blood pressure (p=0.258) in the 3 different times. However, looking at extremes, some patients presented considerably lower diastolic blood pressure in all evaluations, but without significant fluctuation.
Conclusions: :
Our results did not support the idea of significant changes in ocular perfusion pressure during the hemodialysis. It was observed, however, that some patients showed lower diastolic blood pressure, what is worse prognosis factor for patients with glaucoma.
Keywords: intraocular pressure • optic nerve