April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Correlation of Retinal Nerve Fiber Layer (RNFL) and Vascular Distribution in Eyes With Tilted Discs
Author Affiliations & Notes
  • D. S. Kang
    Ophthalmology, Asan Medical Center, Ulsan University, Seoul, Republic of Korea
  • K. Sung
    Ophthalmology, Asan Medical Center, Ulsan University, Seoul, Republic of Korea
  • E. Choi
    Ophthalmology, Asan Medical Center, Ulsan University, Seoul, Republic of Korea
  • S. Lee
    Ophthalmology, Asan Medical Center, Ulsan University, Seoul, Republic of Korea
  • J. Cho
    Ophthalmology, Asan Medical Center, Ulsan University, Seoul, Republic of Korea
  • M. S. Kook
    Ophthalmology, Asan Medical Center, Ulsan University, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships  D.S. Kang, None; K. Sung, None; E. Choi, None; S. Lee, None; J. Cho, None; M.S. Kook, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 2736. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      D. S. Kang, K. Sung, E. Choi, S. Lee, J. Cho, M. S. Kook; Correlation of Retinal Nerve Fiber Layer (RNFL) and Vascular Distribution in Eyes With Tilted Discs. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2736.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Introduction: : Correlation of Retinal Nerve Fiber Layer (RNFL) and Vascular Distribution in Eyes with Tilted Discs.

Purpose: : To evaluate peripapillary retinal nerve fiber layer (RNFL) distribution relative to peripapillary vascular patterns in eyes with tilted discs with spectral domain Optical Coherence Tomography (SD OCT)(Cirrus OCT, Carl Zeiss Meditech, Dublin, CA).

Design: : Prospective cross-sectional observational study.

Methods: : A total of 115 eyes of 115 subjects were consecutively enrolled in the study, 56 with tilted optic disc insertions and 59 with no evidence of disc tilt. All subjects underwent complete oOphthalmologic examinations including Cirrus OCT. imaging by Macula cube mode and Optic Disc cube mode centered at the disc. The degree of disc tilt was determined from OCT images by calculating the angle formed by retinal pigment epithelial layerRPE endings. The distribution and correlation between vessels and location of thickest RNFL were sought.

Results: : Horizontal and vertical disc tilting were 22.76 ± 9.12 and 12.22 ± 6.03 degrees and 8.28 ± 6.45 vs 4.22 ± 2.66, p<0.001 respectively for the both2 groups. (both , p<0.001). The thickest location of RNFL in the TSNIT graphs were 66.13 ± 14.32 vs 76.36 ± 16.28 degrees, ( p=0.001) for superior and 291.7 ± 21.1 vs 288.9 ± 9.33 degrees (, p=0.368) for inferior arcades. Pearson cCorrelation wasshowed significantce betweenfor arteriolar and venular distributions in the superior hemi-retina (R=0.408, p=0.002) and between arteriolar distribution and thickest RNFL location (R=0.268, p=0.048).

Conclusions: : Eyes with optic disc tilting appeared to be more myopic than controls and to display more temporalization of the vascular arcades and thickest location of RNFL compared to control group. The location of thickest RNFL was significantly correlated to arteriolar distribution for both eyes with tilted discs and controls and to amount of disc tilting in the superior hemi-retina but not in the inferior hemi-retina.

Keywords: imaging/image analysis: clinical • anatomy • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×