April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
High Prevalence of Narrow Angles Among Filipino-American Patients
Author Affiliations & Notes
  • M. I. Seider
    Ophthalmology, University of California - San Francisco, San Francisco, California
  • C. S. Sales
    Ophthalmology, University of California - San Francisco, San Francisco, California
  • R. Y. Lee
    Ophthalmology, University of California - San Francisco, San Francisco, California
  • A. K. Agadzi
    Ophthalmology, University of California - San Francisco, San Francisco, California
  • T. C. Porco
    Ophthalmology, University of California - San Francisco, San Francisco, California
  • R. N. Weinreb
    Hamilton Glaucoma Center, Univ of California-San Diego, La Jolla, California
  • S. C. Lin
    Ophthalmology, University of California - San Francisco, San Francisco, California
  • Footnotes
    Commercial Relationships  M.I. Seider, None; C.S. Sales, None; R.Y. Lee, None; A.K. Agadzi, None; T.C. Porco, None; R.N. Weinreb, None; S.C. Lin, None.
  • Footnotes
    Support  Research to Prevent Blindness, NIH-NEI EY002162 – Core Grant for Vision Research, and That Man May See, Inc.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 2760. doi:
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    • Get Citation

      M. I. Seider, C. S. Sales, R. Y. Lee, A. K. Agadzi, T. C. Porco, R. N. Weinreb, S. C. Lin; High Prevalence of Narrow Angles Among Filipino-American Patients. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2760.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine the prevalence of gonioscopically narrow anterior chamber angles in a Filipino-American clinic population.

Methods: : The records of 122 consecutive, new, self-declared Filipino-American patients examined in a comprehensive ophthalmology clinic in Vallejo, California were reviewed retrospectively. After exclusion, 222 eyes from 112 patients remained for analysis. Data were collected for anterior chamber angle grade as determined by gonioscopy (Shaffer system), age, gender, manifest refraction (spherical equivalent), intraocular pressure (IOP) and cup-to-disk ratio (CDR). Data from both eyes of patients were included and modeled using a standard linear mixed-effects regression. As a comparison, data were also collected from a group of 30 consecutive Caucasian patients from the same clinic. After exclusion, 50 eyes from 25 Caucasian patients remained for comparison.

Results: : At least one eye of 24% of Filipino-American patients had a narrow anterior chamber angle (Shaffer grade ≤ 2), whereas all Caucasian patients had open angles (Shaffer grade 3-4) in both eyes (p=0.004). Filipino-American angle grade significantly decreased with increasingly hyperopic refraction (p=0.007) and larger CDR (p=0.038). Filipino-American women had significantly decreased angle grades compared to men (p=0.028) but angle grade did not vary by IOP or age (all, p≥0.059).

Conclusions: : Narrow anterior chamber angles are highly prevalent in Filipino-American patients in our clinic population.

Keywords: clinical (human) or epidemiologic studies: prevalence/incidence • anterior chamber 
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