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J. S. Mehta, S. S. Chaurasia, F. L. Gimeno, K. Tan, S. Yu, D. T. Tan, R. W. Beuerman; In vivo Real-Time Intraocular Pressure Variations During LASIK Flap Creation. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2876.
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To monitor and compare in vivo real-time intraocular pressure (IOP) in rabbit eyes undergoing LASIK flap creation using microkeratome and femtosecond laser.
13 rabbit eyes in each group underwent LASIK flap creation using Moria M2 microkeratome and Visumax Femtosecond laser. In vivo real-time IOP profile was measured using a 30-gauge needle with IOP catheter sensor inserted into the anterior chamber from the limbus during the surgery.
In vivo real time IOP monitoring was achieved in all cases, showing IOP variations during different phases of LASIK flap creation from docking of the instrument, start of surgery to the end of procedure, and later monitoring the post LASIK stabilization. IOP fluctuations were significantly lower in cornea flaps made with femtosecond laser during suctioning (p=0.0345), cutting (p=0.0009) and suction off (p=0.0008) compared to the microkeratome. In contrast, femtosecond laser requires double the time (p=0.0009 for suctioning and p=0.0001 for cutting) to complete the procedure.
We describe an accurate and reliable setup to measure and record in vivo real-time changes in IOP measurement from the anterior chamber during LASIK. Femtosecond laser exerts less extreme IOP fluctuations with improved chamber stability but requires more procedure time compared to microkeratome.
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