April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
In vivo Real-Time Intraocular Pressure Variations During LASIK Flap Creation
Author Affiliations & Notes
  • J. S. Mehta
    Cornea, Singapore National Eye Center, Singapore Eye Research Institute, Singapore, Singapore
  • S. S. Chaurasia
    Cornea, Singapore Eye Research Institute, Singapore, Singapore
  • F. L. Gimeno
    Cornea, Singapore Eye Research Institute, Singapore, Singapore
  • K. Tan
    Cornea, Singapore Eye Research Institute, Singapore, Singapore
  • S. Yu
    Cornea, Singapore Eye Research Institute, Singapore, Singapore
  • D. T. Tan
    Cornea, Singapore National Eye Center, Singapore Eye Research Institute, Singapore, Singapore
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
  • R. W. Beuerman
    Cornea, Singapore Eye Research Institute, Singapore, Singapore
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
  • Footnotes
    Commercial Relationships  J.S. Mehta, None; S.S. Chaurasia, None; F.L. Gimeno, None; K. Tan, None; S. Yu, None; D.T. Tan, R, R; R.W. Beuerman, None.
  • Footnotes
    Support  NMRC/TCR/002 - SERI/2008 - TCR 621/41/2008
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 2876. doi:
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    • Get Citation

      J. S. Mehta, S. S. Chaurasia, F. L. Gimeno, K. Tan, S. Yu, D. T. Tan, R. W. Beuerman; In vivo Real-Time Intraocular Pressure Variations During LASIK Flap Creation. Invest. Ophthalmol. Vis. Sci. 2010;51(13):2876.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To monitor and compare in vivo real-time intraocular pressure (IOP) in rabbit eyes undergoing LASIK flap creation using microkeratome and femtosecond laser.

Methods: : 13 rabbit eyes in each group underwent LASIK flap creation using Moria M2 microkeratome and Visumax Femtosecond laser. In vivo real-time IOP profile was measured using a 30-gauge needle with IOP catheter sensor inserted into the anterior chamber from the limbus during the surgery.

Results: : In vivo real time IOP monitoring was achieved in all cases, showing IOP variations during different phases of LASIK flap creation from docking of the instrument, start of surgery to the end of procedure, and later monitoring the post LASIK stabilization. IOP fluctuations were significantly lower in cornea flaps made with femtosecond laser during suctioning (p=0.0345), cutting (p=0.0009) and suction off (p=0.0008) compared to the microkeratome. In contrast, femtosecond laser requires double the time (p=0.0009 for suctioning and p=0.0001 for cutting) to complete the procedure.

Conclusions: : We describe an accurate and reliable setup to measure and record in vivo real-time changes in IOP measurement from the anterior chamber during LASIK. Femtosecond laser exerts less extreme IOP fluctuations with improved chamber stability but requires more procedure time compared to microkeratome.

Keywords: refractive surgery: LASIK • intraocular pressure • laser 
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