April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Semi-Chronic Implantation of Artificial Retina by Suprachoroidal Transretinal Stimulation (STS) System in Dogs
Author Affiliations & Notes
  • T. Morimoto
    Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • M. Kamei
    Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • K. Nishida
    Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • H. Sakaguchi
    Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Y. Ikuno
    Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • T. maruo
    Neurosurgery,
    Osaka University Graduate School of Medicine, Suita, Japan
  • H. Kishima
    Neurosurgery,
    Osaka University Graduate School of Medicine, Suita, Japan
  • H. Kanda
    Applied Visual Science,
    Osaka University Graduate School of Medicine, Suita, Japan
  • T. Saitoh
    NIDEK CO LTD, Gamagohri, Japan
  • T. Fujikado
    Applied Visual Science,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Footnotes
    Commercial Relationships  T. Morimoto, None; M. Kamei, None; K. Nishida, None; H. Sakaguchi, None; Y. Ikuno, None; T. maruo, None; H. Kishima, None; H. Kanda, None; T. Saitoh, NIDEK CO LTD, E; T. Fujikado, None.
  • Footnotes
    Support  Health Sciences Research Grants (H19-sensory-001) from the Ministry of Health, Labor and Welfare,
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 3023. doi:
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      T. Morimoto, M. Kamei, K. Nishida, H. Sakaguchi, Y. Ikuno, T. maruo, H. Kishima, H. Kanda, T. Saitoh, T. Fujikado; Semi-Chronic Implantation of Artificial Retina by Suprachoroidal Transretinal Stimulation (STS) System in Dogs. Invest. Ophthalmol. Vis. Sci. 2010;51(13):3023.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To study the feasibility of implantation and biostability of a suprachoroidal transretinal stimulation (STS) system consisting of a microelectrode array and an extraocular microelectric device in dogs.

Methods: : Two beagle dogs were used. Under general anesthesia, an array of 9 microelectrodes was implanted into a scleral pocket, a reference needle electrode was inserted in the vitreous through the limb of sclera and an extraocular device was placed subcutaneously on the surface of right temporalis muscle. 1 month after implantation of this system, funduscopic analysis was performed and the operation of this system was checked by measuring both the voltage of electrical circuit in an extraocular device and the electrical conduction of each electrode.

Results: : The surgical procedures for implantation of the electrode array and the extraocular device were accomplished without serious surgical complications. Both the array and the extraocular device kept a stable fixation in dogs within 1 month. 1 month after implant, funduscopy demonstrated no retinal complication over and around implants. And the system was confirmed to work properly.

Conclusions: : This study demonstrates the feasibility of a surgical procedure for safe implantation of the STS system, and this system proved to be biostable in freely-moving dogs for an observation period of 1 month.

Keywords: retina • retinitis • retinal connections, networks, circuitry 
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