April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Operation of a Wireless Retinal Implant Device With Reverse Telemetry
Author Affiliations & Notes
  • P. Doyle
    Boston VA Research Institute, Boston, Massachusetts
    Center for Innovative Visual Rehabilitation, Boston VA Medical Center, Boston, Massachusetts
  • P. R. Troyk
    Department Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois
    Sigenics, Inc., Chicago, Illinois
  • S. K. Kelly
    Center for Innovative Visual Rehabilitation, Boston VA Medical Center, Boston, Massachusetts
  • D. B. Shire
    Boston VA Medical Center, Ctr for Innovative Visual Rehabilitation, Ithaca, New York
    Cornell Nanofabrication Facility, Cornell University, Ithaca, New York
  • J. L. Wyatt, Jr.
    Research Laboratory of Electronics, Massachusetts Inst of Technology, Cambridge, Massachusetts
  • J. F. Rizzo
    Center for Innovative Visual Rehabilitation, Boston VA Medical Center, Boston, Massachusetts
    Ophthalmology, Mass Eye & Ear Infirmary, Boston, Massachusetts
  • Footnotes
    Commercial Relationships  P. Doyle, None; P.R. Troyk, Sigenics, Inc., F; Sigenics, Inc., I; S.K. Kelly, None; D.B. Shire, None; J.L. Wyatt, Jr., None; J.F. Rizzo, None.
  • Footnotes
    Support  DoD Grant W81XWH-07-I-0671;VA CIVR;TATRC/DoD Grant W81XWH-07-0326
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 3032. doi:https://doi.org/
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      P. Doyle, P. R. Troyk, S. K. Kelly, D. B. Shire, J. L. Wyatt, Jr., J. F. Rizzo; Operation of a Wireless Retinal Implant Device With Reverse Telemetry. Invest. Ophthalmol. Vis. Sci. 2010;51(13):3032. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : This work is related to the efforts of the Boston Retinal Implant Project to develop a sub-retinal prosthesis to restore vision to the blind. The specific purpose of this presentation is to describe the operation of a wireless retinal implant device with reverse telemetry and to present results obtained from its use.

Methods: : A custom Application Specific Integrated Circuit (ASIC) was designed by Sigenics, Inc. and fabricated by X-Fab. This ASIC consists of a 16 channel neurostimulator coupled with wireless power and control circuitry and a wireless feedback channel. The ASIC was fitted into a hermetically sealed titanium case. A flexible polyimide electrode array was attached to feedthrough connectors on outside of the case. Operation of the neurostimulator was verified on the benchtop and via electrode waveform measurements transmitted wirelessly back to the controller.

Results: : The device was tested and calibrated with a simple series R-C load. In-vitro stimulation waveform data shows good correlation between the calibration waveforms measured with an oscilloscope, demonstrating that the reverse telemetry channel can be used to measure electrode impedance.

Conclusions: : The custom ASIC provides a platform for making chronic impedance measurements of electrodes implanted subretinally. Further work is required to improve the accuracy and fidelity of the data reported.

Keywords: retina • age-related macular degeneration • retinal degenerations: hereditary 
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