April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Variable Retinal Oxygen Saturation in Retinal Vein Occlusion
Author Affiliations & Notes
  • S. H. Hardarson
    Ophthalmology, University of Iceland / Landspitali University Hospital, Reykjavik, Iceland
    Oxymap ehf., Reykjavik, Iceland
  • E. Stefansson
    Ophthalmology, University of Iceland / Landspitali University Hospital, Reykjavik, Iceland
  • Footnotes
    Commercial Relationships  S.H. Hardarson, Oxymap, I; Oxymap, E; Oxymap, P; E. Stefansson, Oxymap, I; Oxymap, P.
  • Footnotes
    Support  Icelandic Center for Research (Rannís), Eimskip Univ. Fund, Univ. of Iceland Research Fund, Landspítali-Univ. Hospital Research Fund and Helga Jónsdóttir and Sigurliði Kristjánsson Memorial Fund
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 3449. doi:https://doi.org/
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    • Get Citation

      S. H. Hardarson, E. Stefansson; Variable Retinal Oxygen Saturation in Retinal Vein Occlusion. Invest. Ophthalmol. Vis. Sci. 2010;51(13):3449. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To test whether retinal vessel oxygen saturation is affectedin patients with branch or central retinal vein occlusion (BRVOor CRVO).

 
Methods:
 

Oxygen saturation was measured in retinal blood vessels in 11patients with BRVO and 10 patients with CRVO. The retinal oximeteris based on a fundus camera. It measures light absorbance ofretinal vessels at 586nm and 605nm and calculates hemoglobinoxygen saturation. Mean oxygen saturation was calculated for1st and 2nd degree arterioles and venules in both eyes of eachpatient.

 
Results:
 

The table shows oxygen saturation in patients with BRVO. Mean±SD. In CRVO patients, venular oxygen saturationwas 49±12% in CRVO eyes and 65±6% in fellow eyes(n=8, p=0.003). Corresponding values for retinal arterioleswere 99±3% and 99±6% (n=8). 

 

 
Conclusions:
 

Oxygen saturation in retinal venules is significantly lowerin patients with CRVO, when compared with healthy fellow eyes.Venular saturation is highly variable between patients in bothBRVO and CRVO. This may reflect variable completeness of occlusion,variable degrees of recanalization, collateral circulation ortissue atrophy.

 
Keywords: oxygen • vascular occlusion/vascular occlusive disease • imaging/image analysis: clinical 
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