Abstract
Purpose: :
To report our experience with photodynamic therapy of retinal vasoproliferative tumors.
Methods: :
The charts of patients with vasoproliferative tumor treated with photodynamic therapy (PDT) were reviewed. The PDT was administered using standard parameters as for macular choroidal neovascularization.
Results: :
A 61-year-old woman had an inferior 2.4 mm-thick tumor in the left eye with visual acuity of 6/7.5; 14 months later the visual acuity was unchanged and the tumor regressed to 1.2 mm with reduced exudation. A 59-year-old man presented with visual acuity of 6/12 in the left eye caused by cellophane maculopathy secondary to an infero-temporal 1.9 mm tumor. After two sessions of PDT the tumor regressed but the visual acuity remained poor so that epiretinal membrane peel was planned. A 63-year-old man was referred the visual acuity in the left eye reduced to 6/30 as a result of an infero-temporal, exudative, hemorrhagic tumor measuring 2.5 mm in thickness. PDT reduced the exudation but a second course of treatment was considered necessary. A 36-year-old woman presented with visual acuity of 6/9 in the left eye as a result of a temporal tumor measuring 1.3 mm in thickness. Three years later the visual acuity was unchanged and the tumor had regressed to 0.8 mm.
Conclusions: :
Photodynamic induces regression of vasoproliferative tumour with resolution of exudation but may need to be repeated. Surgical treatment of cellophane maculopathy may be required.
Keywords: tumors • retina • laser