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H. Heimann, B. E. Damato; Photodynamic Therapy of Retinal Vasoproliferative Tumors. Invest. Ophthalmol. Vis. Sci. 2010;51(13):3508.
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© ARVO (1962-2015); The Authors (2016-present)
To report our experience with photodynamic therapy of retinal vasoproliferative tumors.
The charts of patients with vasoproliferative tumor treated with photodynamic therapy (PDT) were reviewed. The PDT was administered using standard parameters as for macular choroidal neovascularization.
A 61-year-old woman had an inferior 2.4 mm-thick tumor in the left eye with visual acuity of 6/7.5; 14 months later the visual acuity was unchanged and the tumor regressed to 1.2 mm with reduced exudation. A 59-year-old man presented with visual acuity of 6/12 in the left eye caused by cellophane maculopathy secondary to an infero-temporal 1.9 mm tumor. After two sessions of PDT the tumor regressed but the visual acuity remained poor so that epiretinal membrane peel was planned. A 63-year-old man was referred the visual acuity in the left eye reduced to 6/30 as a result of an infero-temporal, exudative, hemorrhagic tumor measuring 2.5 mm in thickness. PDT reduced the exudation but a second course of treatment was considered necessary. A 36-year-old woman presented with visual acuity of 6/9 in the left eye as a result of a temporal tumor measuring 1.3 mm in thickness. Three years later the visual acuity was unchanged and the tumor had regressed to 0.8 mm.
Photodynamic induces regression of vasoproliferative tumour with resolution of exudation but may need to be repeated. Surgical treatment of cellophane maculopathy may be required.
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