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V. De-Juan, J. Herreras, I. Perez, A. Morejon, A. del Rio, I. Fernandez, G. Rodriguez, R. Martin; Stabilization of Refraction and Corneal Swelling After Cataract Surgery. Invest. Ophthalmol. Vis. Sci. 2010;51(13):3941.
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To determine the earliest time after cataract surgery that the objective refraction and corneal swelling are stable.
Automated refraction (ARK-30, Nidek) and central corneal thickness (CCT) (Orbscan II, Bausch & Lomb) were monitored in 74 eyes of 45 patients (64.4% female, mean age 65.11±13.55 years) before undergoing uncomplicated cataract surgery (baseline visit) and 4 weeks after surgery. This prospective study included 5 follow up visits: at 24 hours (V1), 1st (V2), 2nd (V3), 3rd (V4) and 4th (V5) week. The stabilization of sphere refraction was analyzed by MANOVA and this value was associated with corneal swelling using a random effects model.
Mean sphere value before surgery was -3.51±6.72 D (95% confidence interval (95%CI) from -5.12 to -1.89) and CCT was (547.17 ± 35.91 95%CI 538.73 to 555.60). Stabilization of sphere refraction occurs at V4, with higher change between V1 and V2 (p=0.0027). No differences in sphere refraction were found between V2 and V3 (p=0.8554) or between V4 and V5 (p=0.5869). Stabilization of corneal swelling occurs at V4, with differences between V1 and V2 (p<0.0001), V2 and V3 (p=0.0021) and V3 and V4 (p=0.0368). No differences in corneal swelling were found between V4 and V5 (p=0.6627) (Figure 1).
Sphere refraction and corneal swelling stabilize in the 3rd week after uncomplicated cataract surgery.
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