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W. Huang, D. Wang, Y. Zheng, M. He; Intraocular Pressure and Central Corneal Thickness in Elderly Chinese: The Liwan Eye Study. Invest. Ophthalmol. Vis. Sci. 2010;51(13):3983.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the distribution of central corneal thickness (CCT), intraocular pressure (IOP) and their determinants in elderly Chinese.
CCT was measured using both optical and A-mode ultrasound pachymetry. IOP was measured with Tonopen. Refraction error (RE) and corneal curvature radius (CR) were measured by an autorefractor. Axial length (AL) was obtained by the same A-scan with a biometric probe. History of systemic hypertension (HTN) and diabetes (DM) was collected by a standard questionnaire. Body mass index (BMI) was calculated as weight divided by square of the height. Data were presented for the right eyes.
Among 1405 participants in the study, 1185 right eyes were available for the analysis. The mean values of optical corneal thickness (OCCT), ultrasound corneal thickness (UCCT) and IOP were 512.0±28.5 µm, 541.8±30.7 µm and 15.2±2.9 mmHg, respectively. In the multiple regression models, CCT decreased with age (β=-0.44, P<0.001) and increased in people with greater CR (β=14.08, P<0.001) and DM (β=7.58, P=0.049). IOP was positively associated with CCT (β=0.02, P<0.001), BMI (β=0.14, P<0.001) and HTN (β=0.68, P=0.002).
The distribution of CCT and IOP in this study is similar with the majority of East Asian populations when the method of measurement is taken into consideration.
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