April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Intraocular Pressure and Central Corneal Thickness in Elderly Chinese: The Liwan Eye Study
Author Affiliations & Notes
  • W. Huang
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • D. Wang
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • Y. Zheng
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • M. He
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • Footnotes
    Commercial Relationships  W. Huang, None; D. Wang, None; Y. Zheng, None; M. He, None.
  • Footnotes
    Support  Supported by Program for New Century Excellent Talents in University, National Ministry of Education NCET-06-0720 (MH), Scientific and Technology Foundation of Guangdong Province 2005B30901008 (MH) an
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 3983. doi:https://doi.org/
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      W. Huang, D. Wang, Y. Zheng, M. He; Intraocular Pressure and Central Corneal Thickness in Elderly Chinese: The Liwan Eye Study. Invest. Ophthalmol. Vis. Sci. 2010;51(13):3983. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To describe the distribution of central corneal thickness (CCT), intraocular pressure (IOP) and their determinants in elderly Chinese.

Methods: : CCT was measured using both optical and A-mode ultrasound pachymetry. IOP was measured with Tonopen. Refraction error (RE) and corneal curvature radius (CR) were measured by an autorefractor. Axial length (AL) was obtained by the same A-scan with a biometric probe. History of systemic hypertension (HTN) and diabetes (DM) was collected by a standard questionnaire. Body mass index (BMI) was calculated as weight divided by square of the height. Data were presented for the right eyes.

Results: : Among 1405 participants in the study, 1185 right eyes were available for the analysis. The mean values of optical corneal thickness (OCCT), ultrasound corneal thickness (UCCT) and IOP were 512.0±28.5 µm, 541.8±30.7 µm and 15.2±2.9 mmHg, respectively. In the multiple regression models, CCT decreased with age (β=-0.44, P<0.001) and increased in people with greater CR (β=14.08, P<0.001) and DM (β=7.58, P=0.049). IOP was positively associated with CCT (β=0.02, P<0.001), BMI (β=0.14, P<0.001) and HTN (β=0.68, P=0.002).

Conclusions: : The distribution of CCT and IOP in this study is similar with the majority of East Asian populations when the method of measurement is taken into consideration.

Keywords: clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • intraocular pressure • cornea: clinical science 
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