April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Myopia as a Risk Factor for Progression of Visual Field Loss in Young Patients With Primary Open-Angle Glaucoma
Author Affiliations & Notes
  • Y. Tamura
    Ophthalmology, Kinki University School of Medicine, Osaka, Japan
  • C. Matsumoto
    Ophthalmology, Kinki University School of Medicine, Osaka, Japan
  • S. Okuyama
    Ophthalmology, Kinki University School of Medicine, Osaka, Japan
  • S. Takada
    Ophthalmology, Kinki University School of Medicine, Osaka, Japan
  • F. Tanabe
    Ophthalmology, Kinki University School of Medicine, Osaka, Japan
  • S. Hashimoto
    Ophthalmology, Kinki University School of Medicine, Osaka, Japan
  • E. Arimura
    Ophthalmology, Kinki University School of Medicine, Sakai Hospital, Osaka, Japan
  • Y. Shimomura
    Ophthalmology, Kinki University School of Medicine, Osaka, Japan
  • Footnotes
    Commercial Relationships  Y. Tamura, None; C. Matsumoto, None; S. Okuyama, None; S. Takada, None; F. Tanabe, None; S. Hashimoto, None; E. Arimura, None; Y. Shimomura, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 4027. doi:
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      Y. Tamura, C. Matsumoto, S. Okuyama, S. Takada, F. Tanabe, S. Hashimoto, E. Arimura, Y. Shimomura; Myopia as a Risk Factor for Progression of Visual Field Loss in Young Patients With Primary Open-Angle Glaucoma. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4027.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To demonstrate the clinical characteristics of primary open-angle glaucoma (POAG) in patients under 40 years of age.

Methods: : Subjects in this retrospective study were 51 eyes of 51 patients (43 POAG, 1 POAG suspect and 7 ocular hypertension (OH)) whose initial visits to our clinic were under 40 (range: 9.7 - 39.6) years of age and follow-up periods were longer than 4 (range: 4.1-24.4) years. All of them had 5 or more reliable visual field test results using Octopus program G2 normal strategy. We evaluated the effect of age and myopia on the changes in refraction as spherical equivalent (SE), the ratio of the distance between center of the disc and the fovea (DM) to the disc diameter (DD) (DM/DD ratio) on fundus photograph, mean defects (MD) in the whole field and the clusters of program G2 with Eye SuiteTM Perimetry (HAAG-STREIT).

Results: : The DM/DD ratio increased with the advance of myopia in patients under 20 years of age. In comparison with 25 eyes with the initial SE > -3D to 26 eyes with the initial SE ≤-3D, the clusters with significant deterioration of MD were showed more frequently in moderate or high myopic eyes than the others. In eyes with the initial SE ≤-3D, the deterioration of MD in the lower cluster adjacent of fixation point were less frequently than those in the other clusters.

Conclusions: : Young patients under 20 years old with POAG, POAG suspects or OH can have substantial changes in the disc shape and refraction. The risk for and the pattern of the progression of the visual field loss should be taken into consideration in young myopic patients with POAG.

Keywords: myopia • visual fields • optic disc 
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