April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Assessment of Paramacular Sensitivity in Patients With Retinitis Pigmentosa
Author Affiliations & Notes
  • D. Shimizu
    Chiba university hospital, Chiba-city,chu-o-ku, Japan
  • T. Takeshi
    Chiba University Hospital, Chiba-City,Chu-o-ku, Japan
  • A. Hagiwara
    Chiba University Hospital, Chiba-City,Chu-o-ku, Japan
  • A. Tawada
    Chiba University Hospital, Chiba-City,Chu-o-ku, Japan
  • S. Yamamoto
    Chiba University Hospital, Chiba-City,Chu-o-ku, Japan
  • Footnotes
    Commercial Relationships  D. Shimizu, None; T. Takeshi, None; A. Hagiwara, None; A. Tawada, None; S. Yamamoto, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 4053. doi:
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    • Get Citation

      D. Shimizu, T. Takeshi, A. Hagiwara, A. Tawada, S. Yamamoto; Assessment of Paramacular Sensitivity in Patients With Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4053.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : We have reported that the paramacular sensitivity (PMS) determined by microperimetry-1 (MP-1, Nedek, Japan) was significantly correlated with the visual acuity in patients with retinitis pigmentosa (RP). The purpose of this study was to determine whether PMS can be used to assess the visual condition in RP patients.

Methods: : Thirty eyes of 15 typical RP patients (mean age, 51 years; range, 26 to 62 years) who visited Chiba University Hospital from January to May in 2009 were studied. The PMS was calculated as the mean sensitivity of the 16 sites in the central 2 to 10 degrees of the MP-1. We compared the PMS to the visual acuity, the sensitivity in the central 2 degrees of the MP-1, results of the 10 -2 program of the Humphrey field analyzer (HFA), and results of Goldmann perimetry (GP).

Results: : The PMS was strongly correlated (correlation ratio >0.85) to the other visual functions. For eyes with a PMS <10 dB, the mean deviations of the HFA were not altered significantly. For eyes with a PMS <20 dB, there was considerable variation in the PMS in the central 2 degrees.

Conclusions: : The PMS can be used to assess the visual status of RP patients. This is important because RP patients can often have good visual acuity even if other visual functions are severely impaired. The PMS of the MP-1 may measure visual functions that are not related to the visual acuity.

Keywords: retinal degenerations: hereditary • visual fields 
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