Abstract
Purpose: :
To assess macular structural changes by means of Spectral-Domain optical coherence tomography (SD-OCT) in patients with subclinical maculopathy after penetrating keratoplasty (PPK).
Methods: :
Prospective, descriptive case series. We include patients with clinical diagnosis of corneal ectasia scheduled for penetrating keratoplasty. All patients underwent a complete eye examination which includes the following: the best corrected visual acuity (BCVA) assessment by protocol ETDRS refraction and a SD-OCT without pharmacological mydriasis to measure the central macular thickness (CRT) and retinal architecture changes. The examination was performed at baseline, 1 day and 1 week after PPK. Statistical analysis was made by means of non-parametric statistic.
Results: :
A total of 10 patients were included in the study (4 males, 6 females). The mean age was 35.6 years-of-age (Range: 22 to 53 ). Nine patients had keratoconus and 1 had ectasia post-Lasik. At baseline, the mean CRT was 241.8µm (range 141µm to 332µm), One day after PPK the mean CRT was 253.4µm (range 203µm to 306µm). One week after PPK the mean CRT was 244.2µm (range 167µm to 326µm). Retinochoroidal folds were detected in 8 patients (80%) one day after surgery.
Conclusions: :
There are no difference in the CRT and BCVA before and one week after PPK. SD-OCT is a safe-noninvasive diagnostic method for detection of subclinical maculopathy after PPK even without pharmacological mydriasis.
Keywords: detection • macula/fovea • imaging/image analysis: clinical