April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Detection of Macular Changes by Spectral-Domain Optical Coherence Tomography in Patients With Subclinical Maculopathy After Penetrating Keratoplasty: Pilot Study
Author Affiliations & Notes
  • A. Hitos
    Retina, APEC, Distrito Federal, Mexico
  • E. Y. Oregon Miranda
    Fellow in Cornea and Refractive Surgery, Asoc Para Evitar la Ceguera en Mexico, San Lucas, Coyoacan, Mexico
  • V. Morales-Canton
    Retina, Asociacion Para Evitar La Ceguer, Mexico City, Mexico
  • Footnotes
    Commercial Relationships  A. Hitos, None; E.Y. Oregon Miranda, None; V. Morales-Canton, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 4387. doi:
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      A. Hitos, E. Y. Oregon Miranda, V. Morales-Canton; Detection of Macular Changes by Spectral-Domain Optical Coherence Tomography in Patients With Subclinical Maculopathy After Penetrating Keratoplasty: Pilot Study. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4387.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To assess macular structural changes by means of Spectral-Domain optical coherence tomography (SD-OCT) in patients with subclinical maculopathy after penetrating keratoplasty (PPK).

Methods: : Prospective, descriptive case series. We include patients with clinical diagnosis of corneal ectasia scheduled for penetrating keratoplasty. All patients underwent a complete eye examination which includes the following: the best corrected visual acuity (BCVA) assessment by protocol ETDRS refraction and a SD-OCT without pharmacological mydriasis to measure the central macular thickness (CRT) and retinal architecture changes. The examination was performed at baseline, 1 day and 1 week after PPK. Statistical analysis was made by means of non-parametric statistic.

Results: : A total of 10 patients were included in the study (4 males, 6 females). The mean age was 35.6 years-of-age (Range: 22 to 53 ). Nine patients had keratoconus and 1 had ectasia post-Lasik. At baseline, the mean CRT was 241.8µm (range 141µm to 332µm), One day after PPK the mean CRT was 253.4µm (range 203µm to 306µm). One week after PPK the mean CRT was 244.2µm (range 167µm to 326µm). Retinochoroidal folds were detected in 8 patients (80%) one day after surgery.

Conclusions: : There are no difference in the CRT and BCVA before and one week after PPK. SD-OCT is a safe-noninvasive diagnostic method for detection of subclinical maculopathy after PPK even without pharmacological mydriasis.

Keywords: detection • macula/fovea • imaging/image analysis: clinical 
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