Abstract
Purpose: :
To determine the predictive value of selective laser trabeculoplasty (SLT) results in one eye on the contralateral eye.
Methods: :
Retrospective chart review of all cases performed by three surgeons between 2002 and 2008. Inclusion criteria were open-angle glaucoma, age 18 years or older, uncontrolled with maximum tolerable medical therapy, treated with SLT in both eyes, and follow-up for more than 6 months. Success was defined as a decrease in IOP of at least 3 mmHg maintaining through the last follow-up without use of any additional medication or laser or incisional surgical intervention.
Results: :
178 eyes of 89 patients met our inclusion criteria. 67 patients (75.3%) showed the same result, success or failure, in the contralateral eye. Multivariate conditional logistic regression analysis of patients who had a differing results between the two eyes (n=22) showed that pretreatment medication number (p = .030; OR 0.053; 95% C.I. 0.004-0.756), and SLT energy (p = .038; OR <0.001; 95% C.I. 0.000-0.475) were associated with a greater chance of success. In patients whose first eye failed, multivariate Cox proportional hazard analysis comparing those who were successful (n=19) versus failed eyes (n=46) in the second eye showed that a higher baseline IOP (p = .026; hazard ratio(HR) 0.894; 95% C.I. 0.810-0.986) was associated with a greater chance of success.
Conclusions: :
The result of the first eye is predictive of the result in the contralateral eye. If there is a poor response to SLT in one eye, greater baseline antiglaucoma medications, higher baseline IOP, higher laser power were associated with a greater chance of success. Higher treatment energy may be helpful to obtain better outcomes when applying a SLT to the contralateral eye.
Keywords: intraocular pressure