April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
How Effective is High Energy Selective Laser Trabeculoplasty?
Author Affiliations & Notes
  • A. S. Khouri
    Ophthalmology, UMD New Jersey Medical School, Newark, New Jersey
  • T. L. Berezina
    Ophthalmology, UMD New Jersey Medical School, Newark, New Jersey
  • B. Maltzman
    Ophthalmology, UMD New Jersey Medical School, Newark, New Jersey
  • D. Cinotti
    Ophthalmology, UMD New Jersey Medical School, Newark, New Jersey
  • W. Constad
    Ophthalmology, UMD New Jersey Medical School, Newark, New Jersey
  • R. D. Fechtner
    Ophthalmology, UMD New Jersey Medical School, Newark, New Jersey
  • Footnotes
    Commercial Relationships  A.S. Khouri, None; T.L. Berezina, None; B. Maltzman, None; D. Cinotti, None; W. Constad, None; R.D. Fechtner, None.
  • Footnotes
    Support  Research to Prevent Blindness, NY, The New Jersey Lions Eye Research Foundation, NJ and The Glaucoma Research & Education Foundation, NJ
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 4425. doi:
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    • Get Citation

      A. S. Khouri, T. L. Berezina, B. Maltzman, D. Cinotti, W. Constad, R. D. Fechtner; How Effective is High Energy Selective Laser Trabeculoplasty?. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4425.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

Recommended conventional energy level for SLT treatment is just at the threshold of bubble formation. The aim of our study was to evaluate intraocular pressure (IOP) reduction from treatment with conventional energy selective laser trabeculoplasty (C-SLT) and higher energy selective laser trabeculoplasty (HE-SLT) performed in a single practice.

 
Methods:
 

Data from SLT procedures performed in patients requiring additional IOP reduction between 5/2003 and 6/2008 were collected from an electronic medical record (EMR). SLT parameters, IOP and number of glaucoma medications were obtained from the EMR. IOP reduction from baseline was calculated in subjects treated with C-SLT energy (defined as <1.0mJ, mean 0.8+/- 0.1 mJ) and HE-SLT (defined as >1.0 mJ, mean 1.5+/- 0.2 mJ).

 
Results:
 

The C-SLT and HE-SLT groups included 389 and 79 eyes at baseline respectively (mean age 73.2 and 73.6 yrs, ns). SLT treatment was performed 360 degrees in all eyes. Number of applications in C-SLT and HE-SLT were 100.6 and 103.9 respectively (ns). Numbers of medications in the two groups at baseline and after SLT were not statistically different. Baseline IOP was higher in the HE-SLT group (21.7±5.1 mmHg) than in C-SLT (19.3±4.7 mmHg, P<0.05). IOP reductions from baseline were statistically significant in C-SLT and HE-SLT at all time points. Comparisons of IOP reductions from baseline and at months 1, 4 and 8 between C-SLT and HE-SLT are included in the table.

 
Conclusions:
 

Mean reductions in IOP (mmHg) from baseline in the HE-SLT were greater than C-SLT at 1 and 8 months in this cohort of patients. These data were collected from an EMR in a single practice. Longer follow-up of a larger group of matched subjects is needed to better characterize the significance and safety of HE-SLT for IOP reduction.  

 
Keywords: laser • intraocular pressure • outflow: trabecular meshwork 
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