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J. J. Tan, D. F. Chang; Risk Factors Among Cataract Patients for Steroid Response. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4563.
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Elevated intraocular pressure (IOP) is a known complication of topical steroids. This study evaluated the age and axial length of steroid responders following cataract surgery.
A retrospective chart review included 1642 eyes with uncomplicated cataract surgery during a one calendar year period from a single ophthalmology practice. All patients received topical 1% prednisolone acetate postoperatively. In addition to axial length and patient age, the IOP from the following time intervals was recorded: preop, postoperative day 1, and within the first postoperative month. A steroid responder was defined as having an IOP rise > 25% while on topical prednisolone (minimum 28 mmHg) followed by an IOP drop > 25% when prednisolone was discontinued. Steroid responder eyes were then compared to non-responder eyes based on age and axial length.
Thirty eight eyes were diagnosed as steroid responders. Final data analysis is pending, but showed that younger age and longer axial length were associated with a higher risk of steroid response - particularly for an IOP rise to > 40 mmHg.
Young myopes should be more carefully monitored for a postoperative steroid response following uncomplicated cataract surgery.
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