April 2010
Volume 51, Issue 13
ARVO Annual Meeting Abstract  |   April 2010
Risk Factors Among Cataract Patients for Steroid Response
Author Affiliations & Notes
  • J. J. Tan
    Boston University, Boston, Massachusetts
  • D. F. Chang
    UCSF, San Francisco, California
  • Footnotes
    Commercial Relationships  J.J. Tan, None; D.F. Chang, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 4563. doi:
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    • Get Citation

      J. J. Tan, D. F. Chang; Risk Factors Among Cataract Patients for Steroid Response. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4563.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : Elevated intraocular pressure (IOP) is a known complication of topical steroids. This study evaluated the age and axial length of steroid responders following cataract surgery.

Methods: : A retrospective chart review included 1642 eyes with uncomplicated cataract surgery during a one calendar year period from a single ophthalmology practice. All patients received topical 1% prednisolone acetate postoperatively. In addition to axial length and patient age, the IOP from the following time intervals was recorded: preop, postoperative day 1, and within the first postoperative month. A steroid responder was defined as having an IOP rise > 25% while on topical prednisolone (minimum 28 mmHg) followed by an IOP drop > 25% when prednisolone was discontinued. Steroid responder eyes were then compared to non-responder eyes based on age and axial length.

Results: : Thirty eight eyes were diagnosed as steroid responders. Final data analysis is pending, but showed that younger age and longer axial length were associated with a higher risk of steroid response - particularly for an IOP rise to > 40 mmHg.

Conclusions: : Young myopes should be more carefully monitored for a postoperative steroid response following uncomplicated cataract surgery.

Keywords: corticosteroids • intraocular pressure • cataract 

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