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M. T. Higazy, A. I. Sharawy, K. A. Kolkailah, O. Elnahrawy, M. E. Shaheen; Corneal Biomechanics and Intra-Ocular Pressure. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4622.
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To study the effect corneal biomechanical properties effect on IOP measurements, and compare this to Goldman applanation tonometer (GAT) the gold standard.
An observational cross-sectional clinical study, 180 eyes of 94 normal participants were included. All participants underwent IOP measurement by ORA and GAT. Corneal compensated IOP (IOPcc), Goldman related IOPg , corneal hysteresis (CH) and Corneal resistance factor (CRF) were recorded. Statistical analysis of the data was performed
Mean IOP measured by GAT was 14.03±3.00mmHg. ORA measurements for IOPg was 14.55±2.95mmHg. IOPcc ORA measurements was 16.3±3.5mmHg. The recorded values of the GAT and ORA-IOPg were nearly similar indicating accuracy of ORA in measuring IOP. Mean difference between IOPcc and IOPg was 4.7mmHg , and this showed a significant negative correlation with CH. (r= -0.98)
The biomechanical properties of the cornea (CH, CRF) are critical parameters that influence IOP measurements.
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