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R. Gallego-Pinazo, M. Díaz-Llopis, P. Udaondo, D. Salom, R. Dolz-Marco, S. Martínez-Castillo, J. J. García-Medina, V. C. Zanón-Moreno; Feasibility of the HD-Cirrus Retinal Thickness Map in the Guidance of Macular Photocoagulation for Diabetic Macular Edema. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4662.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the efficacy of macular laser photocoagulation (MLP) guided by fluorescein angiography (FA) and by Spectral-Domain OCT (HD-Cirrus) in patients with diabetic macular edema (DME)
20 eyes of 10 patients with DME were included. Baseline examination included BCVA measure (logMAR), HD-Cirrus OCT (Central subfield thickness, CST; retinal volume, RV), and FA. Then, subjects were distributed into two groups: 1. MLP guided by FA (n=10 eyes). In these cases the laser spots location was planned according to the leaking areas evidenced with the FA; 2.MLP guided by HD-Cirrus (n=10 eyes): in these cases the laser spots location was planned according to the retinal thickness map obtained with the OCT (see figure). Three months after MLP patients were re-examined for BCVA, CST and RV.
In the FA-guided MLP group, the mean CST decreased from 394.2 microns at baseline to 303.4 microns by 3 months follow-up (p=0.006). The mean RV decreased from 12.04 to 11.11 mm2 (p=0.006). The mean BCVA improved from 0.41 to 0.27 logMAR (p=0.001).In the OCT-guided MLP group, the mean CST decreased from 425.1 microns at baseline to 298.9 microns by the 3 months follow-up (p=0.001). The mean RV decreased from 12.15 to 10.76 mm2 (p=0.001). The mean BCVA improved from 0.48 to 0.31 logMAR (p=0.003). No statistically significant difference were found between both groups in CST and RV changes (p= 0.854 and 0.424) or visual improvement (p=0.591).
HD-Cirrus retinal thickness map appears to be a useful alternative to FA in the laser spots guidance for macular photocoagulation in diabetic macular edema.
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