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J. Haentzschel, F. Sorgenfrei, L. E. Pillunat; Visual Field Loss in Normal and High Tension Glaucoma With Same Optic Nerve Head Morphologic Characteristics. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4910.
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© ARVO (1962-2015); The Authors (2016-present)
To determine whether the visual field loss in patient with normal tension glaucoma is different from those of high tension glaucoma, with same optic nerve head morphologic characteristics
In a retrospective, case matched study patients with NTG were recruited from our glaucoma database, excluding those with myopia>6dpt, papillary abnormalities, other ocular diseases, amblyopic or central nervous diseases. On the basis of disc area and cup disc ratio were matched patients with NTG to those with HTG on case-by-case basis. Heidelberg retina tomography was used to evaluate the optic disk, ocular micro perfusion with Ocular blood flowmeter (OBF) and Visual field loss with Humphrey 30/2 perimetry.
Twenty-six patients were recruited for the study, 13 eyes with NTG were matched to 13 eyes with HTG. The optic nerve head morphologic characteristics were nearly identical (NTG/HTG: Cup/disk ratio 0,86/0,87 , p=0,165; HRT disc area 2,34/2,34mm², p=0,608; rim area 1,08/1,04mm², p=0,510; Mean RNFL thickness 0,20/0,19, p=0,774). The visual field loss were in HTG significant higher compared to the eyes with NTG (NTG/HTG MD -2,6/-11,86dB, p=0,01; PSD 4,02/8,3dB, p=0,049 [probility score <5% 3,7/4,6,p=0,53; <2% 1,3/3,0,p=0,126, <1% 0,9/3,4,p=0,01, <0,5% 4,6/24,61, p=0,001]). The micro perfusion (OBF) were similar in both groups (NTG/HTG OBF 19,86/19,36 µl/sec, p=0,738).
The same optic nerve head damage seems to result in higher visual field loss in patients with high tension glaucoma compared to patients with normal tension glaucoma.
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