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M. M. Cordeiro Barbosa, F. Hirai, A. Moriyama, A. Hofling-Lima; Pachymetric and Topographic Changings Following Corneal Collagen Crosslinking for Edema. Invest. Ophthalmol. Vis. Sci. 2010;51(13):4997.
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© ARVO (1962-2015); The Authors (2016-present)
Corneal collagen cross-linking technique consists of photopolymerization of the stromal fibers influencing the swelling behavior of the tissue. The purpose of this study is to investigate the pachymetric and topographic changes of collagen cross-linking in corneas with edema due to endothelial dysfunction.
Interventional case series included 5 eyes of 5 consecutive patients with corneal edema for at least 4 months. Central corneal thickness and anterior sagital curvature were measured preoperatively, three month, six month and a year after corneal cross-linking by Pentacam (Oculus Inc, Lynnwood, Washington, USA)
Mean central corneal thickness and mean K value decreased after corneal cross-linking: 638µm; 569µm; 584µm; 620µm and 42,95D; 40,92D; 40,55D; 40,95D for preoperative, 3-month, 6-month and 1-year follow-up, respectively.
Corneal cross-linking showed to reduce temporarily corneal thickness along with a maintained flattening of the anterior corneal curvature.
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