April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Long Term Visual Outcomes of Lens-Sparing Vitrectomy for Retinopathy of Prematurity
Author Affiliations & Notes
  • R. Singh
    Alkek Eye Institute, Baylor College of Medicine, Houston, Texas
  • D. Reddy
    Department of Ophthalmology, University of Texas Medical Branch at Galveston, Galveston, Texas
  • A. Barkmeier
    Alkek Eye Institute, Baylor College of Medicine, Houston, Texas
  • E. Holz
    Alkek Eye Institute, Baylor College of Medicine, Houston, Texas
  • P. Carvounis
    Alkek Eye Institute, Baylor College of Medicine, Houston, Texas
  • Footnotes
    Commercial Relationships  R. Singh, None; D. Reddy, None; A. Barkmeier, None; E. Holz, None; P. Carvounis, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 5225. doi:
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      R. Singh, D. Reddy, A. Barkmeier, E. Holz, P. Carvounis; Long Term Visual Outcomes of Lens-Sparing Vitrectomy for Retinopathy of Prematurity. Invest. Ophthalmol. Vis. Sci. 2010;51(13):5225.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To compare the long term visual outcomes of lens-sparing vitrectomy (LSV) with and without scleral buckling (SB) for Stage 4A, 4B and 5 retinopathy of prematurity.

Methods: : Infants with ROP who underwent LSV by a single surgeon at a tertiary referral center between 1998 and 2004 were included. The primary endpoint was visual acuity at least 5 years after surgical intervention. Anatomic success, defined as complete retinal attachment, was evaluated as a secondary end point. Patients who underwent lensectomy or did not have a documented visual acuity five years post operatively were excluded.

Results: : Sixty of 124 patients with retinopathy of prematurity requiring surgical intervention for stage 4A, 4B and 5 between 1998 to 2004 underwent LSV. Follow up of at least 5 years was available for 18 eyes of 13 patients.The group that underwent LSV with SB comprised 13 eyes of 10 patients (9 Stage 4A, 3 Stage 4B, 1 Stage 5). The average length of follow up was 8.15 years, and the average logMAR visual acuity in this group was 1.176 (Snellen equivalent 20/300) for patients with measurable visual acuity. One patient with severe developmental delay was able to fix and follow in both eyes, and 2 eyes had light perception only. Only 1 eye was not attached, and the final visual acuity in this patient was NLP at 10 years of age.The group that underwent LSV without SB comprised 5 eyes or 3 patients (all with Stage 4A disease). The average length of follow up was 5.8 years, and the average logMAR visual acuity was 1.61 (Snellen equivalent 20/815) for the 4 eyes with form vision while 1 eye had light perception only. Anatomic success was noted in all 5 cases.There were no statistically significant differences in the final logMAR visual acuity (paired t-test, p = .331) or long-term anatomic attachment rates (paired t-test, p = .52) between the two groups.

Conclusions: : Long term visual outcomes of LSV are similar with or without SB. SB should be employed without concern about adverse effect on visual outcomes in the long-term in cases that may benefit from its use. Additionally, parents may be informed that while LSV is necessary to preserve vision the resulting vision is often limited.

Keywords: retinopathy of prematurity 
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