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S. Laib, C. Ehrardt, P. Bourgin, C. Speeg-schatz, T. Bourcier; Chronic Glaucoma and Floppy Eyelid Syndrome in Patients Suffering Obstructive Sleep Apnea. Invest. Ophthalmol. Vis. Sci. 2010;51(13):5368.
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Studies suggest an association between obstructive sleep apnea ( OSA) and eyes diseases such as floppy eyelid syndrome ( FES), chronic glaucoma, nonarteritic anterior ischemic optic neuropathy (NAION) and keratoconus. However, results of these studies are contradictory. The objective of our study is to determine if there is or not an association between eye diseases and OSA.
We realized a monocentric prospective study, including 140 patients consulting for respiratory sleep disorders for which a complete ophthalmological examination was realized ( visual acuity, intraocular pressure, corneal thickness, OCT fibers analysis, corneal topography, visual field Hymphrey 30-2 and an eyelid examination). The patients were distributed in different groups according to the severity of the sleep respiratory disorder (normal, light, moderate and severe).
Preliminary result indicate a frequency of 20 % FES on total population with higher prevalence in the light, moderate and severe groups of OSA (40 %) there is a significant statistic (p=0.016) relation between floppy and time desaturation under 90 % of oxygen. We observe 7 % of chronic glaucoma on total population distributed fairly between normal patients and patients suffering OSA ( p=0.65 ). We did not find case of NAION and keratoconus.Discussion:The correlation is statistically significant ( p=0.016 ) between floppy and desaturation in oxygen suggest an association between eye and obstructive sleep diseases. We have prevalence of 7 % of glaucoma what is upper to the national average probably due to the small population analyzed. We did not find NOIAA and keratoconus due to prevalence of these diseases.
The analysis of 140 patients is being and we can really determined an association between sleep diseases and the eye diseases. A significant association would report the importance of the collaboration between ophtalmologists and doctors of sleep.
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