April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Intraoperative OCT (iOCT) for Anterior and Posterior Segment Surgery
Author Affiliations & Notes
  • M. Mueller
    Department of Ophthalmology,
    University of Luebeck, Luebeck, Germany
  • P. Steven
    Department of Ophthalmology,
    University of Luebeck, Luebeck, Germany
  • E. Lankenau
    Institute of Biomedical Optics,
    University of Luebeck, Luebeck, Germany
    Optomedical Technologies, GmbH, Luebeck, Germany
  • M. Krug
    Institute of Biomedical Optics,
    University of Luebeck, Luebeck, Germany
  • E. Acidereli
    Institute of Biomedical Optics,
    University of Luebeck, Luebeck, Germany
  • S. Oelckers
    Optomedical Technologies, GmbH, Luebeck, Germany
    Möller-Wedel GmbH, Wedel, Germany
  • R. Birngruber
    Institute of Biomedical Optics,
    University of Luebeck, Luebeck, Germany
  • S. Grisanti
    Department of Ophthalmology,
    University of Luebeck, Luebeck, Germany
  • G. Hüttmann
    Institute of Biomedical Optics,
    University of Luebeck, Luebeck, Germany
  • Luebeck Oct Study Group
    University of Luebeck, Luebeck, Germany
  • Footnotes
    Commercial Relationships  M. Mueller, None; P. Steven, None; E. Lankenau, OPTOMEDICAL TECHNOLOGIES, I; OPTOMEDICAL TECHNOLOGIES, P; M. Krug, None; E. Acidereli, None; S. Oelckers, OPTOMEDICAL TECHNOLOGIES, I; Möller-Wedel GmbH, E; OPTOMEDICAL TECHNOLOGIES, P; R. Birngruber, None; S. Grisanti, None; G. Hüttmann, Möller-Wedel, F; Thorlabs HL AG, F; Thorlabs HL AG, C.
  • Footnotes
    Support  Medical Technology Grant, University of Luebeck and MÖLLER-WEDEL, GmbH, Wedel, Germany
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 5817. doi:
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      M. Mueller, P. Steven, E. Lankenau, M. Krug, E. Acidereli, S. Oelckers, R. Birngruber, S. Grisanti, G. Hüttmann, Luebeck Oct Study Group; Intraoperative OCT (iOCT) for Anterior and Posterior Segment Surgery. Invest. Ophthalmol. Vis. Sci. 2010;51(13):5817.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Evaluation of a new surgical microscope-mounted OCT-Camera.Patients and

Methods: : In a pilot study, pig eyes, healthy volunteers and patients were examined with the new developed OCT-Camera (M-W, in cooperation with OpMedT) mounted on a surgical microscope (Hi-R 900, M-W) with microscope external display (MEDIS, M-W) with non-contact 90D (EIBOS, M-W) or contact vitrectomy flat lens (DORC; Zuidland, Netherlands) for posterior segment viewing. The OCT-Camera (central wavelength 840nm) had a measuring depth of 5.2 mm and width dependant on the zoom of the microscope with a minimum of 5 mm at maximum zoom. Acquisition time was 10000 A-scans/s. Anterior and posterior segment manipulation was simulated on freshly dissected pig eyes, healthy volunteers and patients undergoing anterior and posterior segment surgery. Image stacks, en-face OCT and 2D-real time imaging with additional volume scans were recorded.

Results: : OCT-Camera enabled simultaneously real-time OCT imaging of anterior and posterior segment surgery. Corneal incisions, preparation of deep corneal lamellar incisions and gripping of retinal structures were simulated in freshly dissected pig eyes to optimize OCT-settings. White-to-white anterior chamber scans and central retinal images of healthy volunteers were analyzed in real-time and reconstructed in 3D and 2D over time. Prior, during and after surgical removal, pathologies such as epiretinal membranes, macular holes and vitreomacular tractions could be visualized in high-resolution. Cataract corneal incisions, trabeculectomy flaps and corneal sutures were recorded online. Surgical instruments could be localized during manipulation.

Conclusions: : iOCT with the OCT-Camera enables high-resolution imaging. It simplifies localization of instruments in relation to ocular structures and enables direct intraoperative control of intended therapy.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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