April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Five-Year Changes of Ocular Biometry and Gonioscopic Angle Width in Elderly Chinese: The Liwan Eye Study
Author Affiliations & Notes
  • M. He
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • S. Huang
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • Y. Jiang
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • Q. Yin
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • Y. Zeng
    Preventive Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • Footnotes
    Commercial Relationships  M. He, None; S. Huang, None; Y. Jiang, None; Q. Yin, None; Y. Zeng, None.
  • Footnotes
    Support  the State Key Laboratory Fund of Zhongshan Ophthalmic Center, Sun Yat-Sen University Clinical Research 5010 Program, Excellent Talents in University, National Ministry of Education NCET-06-0720;
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 5831. doi:
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      M. He, S. Huang, Y. Jiang, Q. Yin, Y. Zeng; Five-Year Changes of Ocular Biometry and Gonioscopic Angle Width in Elderly Chinese: The Liwan Eye Study. Invest. Ophthalmol. Vis. Sci. 2010;51(13):5831.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To our best knowledge, the longitudinal changes of ocular biometry in the population have not been documented. In this report, we attempt to report 5-year longitudinal changes and their impacts on the drainage angle width in the Chinese aged 50 years and over identified from the Liwan Eye Study.

Methods: : The subjects who participating the Liwan Eye Study in 2004 were invited for a comprehensive eye examination in 2009. Ocular biometry was measured by A-mode applanation ultrasound at sitting position. Gonioscopy was performed by using a Goldmann-type, one-mirror lens. These two examinations were performed for all the subjects by the same examiners using the same equipment and protocol at baseline and follow up visit. Only the phakic right eyes were included for the analysis.

Results: : Of 1081 subjects eligible for 2009 examination (after excluding 177 died, 147 permanently moved out from the area), 874 people (80.9%) attended the follow-up examination. Among 818 phakic right eyes, the axial length increased by 0.14+/-0.31 mm (paired t test, P<0.001), anterior chamber depth decreased by 0.02+/-0.26mm (P<0.001), lens thickness increased by 0.56+/-0.70mm (P<0.001). The mean Shaffer grades decreased by 0.13 grades whereas the Shaffer angle width in 247 eyes (30.2%) became smaller.

Conclusions: : This preliminary analysis suggests that the drainage angles become narrower, the lens become thicker whereas the anterior chamber depth does not change significantly in adults over 5 years.

Keywords: anterior segment • clinical (human) or epidemiologic studies: natural history • clinical (human) or epidemiologic studies: prevalence/incidence 
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