April 2010
Volume 51, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2010
Six Year Incidence of Angle Closure Disease in a Rural South Indian Population
Author Affiliations & Notes
  • R. J. George
    Glaucoma, Medical Research Foundation, Chennai, India
  • S. V. Ramesh
    Glaucoma, Medical Research Foundation, Chennai, India
  • V. Lokapavani
    Glaucoma, Medical Research Foundation, Chennai, India
  • A. Rashima
    Glaucoma, Medical Research Foundation, Chennai, India
  • N. Choudhury
    Glaucoma, Medical Research Foundation, Chennai, India
  • M. Pandey
    Glaucoma, Medical Research Foundation, Chennai, India
  • V. Lingam
    Glaucoma, Medical Research Foundation, Chennai, India
  • Footnotes
    Commercial Relationships  R.J. George, None; S.V. Ramesh, None; V. Lokapavani, None; A. Rashima, None; N. Choudhury, None; M. Pandey, None; V. Lingam, None.
  • Footnotes
    Support  Chennai willingdon Corporate Foundation
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 5832. doi:
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      R. J. George, S. V. Ramesh, V. Lokapavani, A. Rashima, N. Choudhury, M. Pandey, V. Lingam; Six Year Incidence of Angle Closure Disease in a Rural South Indian Population. Invest. Ophthalmol. Vis. Sci. 2010;51(13):5832.

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Abstract

Purpose: : To estimate the six year incidence of angle closure disease in a population based cohort from rural South India.

Methods: : The Chennai Eye Diseases Incidence Survey (CEDIS) examined 2504 subjects, aged 45 years and older ,between 2007-2009 examined in the Chennai Glaucoma Study from 2001-2004. All subjects underwent a comprehensive glaucoma evaluation including IOP measurement, 4 mirror gonioscopy, Biometry , visual field evaluation and stereoscopic optics disc assessment. Of them 1530 bilaterally phakic subjects with open angles on gonioscopy at baseline were included. Angle closure disease was diagnosed based on modified international Society of Geographic and Epidemiologic Ophthalmology ISGEO recommendations.

Results: : Forty three persons ( 2.81 % ) (95% CI: 1.99,3.64 %) were diagnosed to have primary angle closure disease in at least one eye ( 34 had bilateral disease). On multivariate analysis decreasing central anterior chamber depth was the only risk factor for disease.

Conclusions: : Anterior chamber depth was the only predictor for angle closure disease incidence in this rural south Indian population.

Keywords: clinical (human) or epidemiologic studies: prevalence/incidence 
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