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G. Barreau, M. Mounier, J.-P. Adenis, P.-Y. Robert; Intra-Cameral Injection of Cefuroxim at the End of Cataract Surgery Decreases the Incidence of Post- Surgery Endophtalmitis. Invest. Ophthalmol. Vis. Sci. 2010;51(13):6035.
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To study the benefits of intra-cameral injection of cefuroxim at the end of cataract surgery on the incidence of post-surgery endophtalmitis.
We designed a study including 5184 patients operated of cataract between april 2003 and june 2008. The intracameral injection process started in june 2006.Every patient operated from simple cataract surgery in our unit has been included in the study. Pre-operative data, such as, allergy or endophtalmitis and peri-operative data such as surgical methods (colorants, ring, hands washing technic, surgical time, surgeon, operating room) were prospectively recorded.
Respectively, the incidence of endophtalmitis before and after cefuroxim intracamerular injection was 36 out of 2875 operated before and one out of 2309 after (p<0,001).None of the surgical risk factors we considered has been significantly involved in increasing the incidence of endophtalmitis.No allergic reaction has been reported.
The intracamerular cefuroxim injection at the end of cataract surgery significantly decreases the incidence of endophtalmitis
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