Abstract
Purpose: :
To report causative organisms and the associated visual acuity outcomes in patients with delayed-onset, bleb-associated endophthalmitis.
Methods: :
Retrospective consecutive case series. Patients who were treated at the Bascom Palmer Eye institute for delayed-onset, bleb-associated endophthalmitis between January 1, 1996 through July 1, 2008 were included in this study. Culture results and visual acuity outcomes were analyzed.
Results: :
A total of 65 eyes from 63 patients were identified. 85% (55/65) had positive intraocular cultures, and 15% (10/65) were culture negative. 14% (9/65) had polymicrobial infections. All organisms were sensitive to the intravitreal antibiotics clinically administered. Visual acuity outcomes of ≥20/400 were achieved in the following percentages of eyes: 40% (8/20) with Streptococcus species, 73% (8/11) with coagulase-negative Staphylococcus, 63% (5/8) with Staphylococcus aureus, 20% (1/5) with Enterococcus species, 80% (4/5) with Moraxella species, 25% (1/4) with Pseudomonas aeruginosa, 50% (4/8) with other gram-negative bacteria, and 70% (7/10) of culture negative eyes.
Conclusions: :
In the current study, better visual acuity outcomes were associated with Staphylococcal species, Moraxella species, and culture negative eyes compared to eyes with Streptococcus species, Enterococcus species, and Pseudomonas aeruginosa.
Keywords: endophthalmitis • bacterial disease