April 2010
Volume 51, Issue 13
ARVO Annual Meeting Abstract  |   April 2010
The Impact of Neonatal Endophthalmitis on Hospital Charges
Author Affiliations & Notes
  • A. A. Moshfeghi
    Vitreoretinal Surgery & Diseases, Bascom Palmer Eye Institute, Palm Beach Gardens, Florida
  • D. M. Moshfeghi
    Ophthalmology, Stanford University, Menlo Park, California
  • T. Hernandez-Boussard
    Stanford University School of Medicine, Palo Alto, California
  • R. A. Charalel
    Stanford University School of Medicine, Palo Alto, California
  • J. M. Morton
    Stanford University School of Medicine, Palo Alto, California
  • Footnotes
    Commercial Relationships  A.A. Moshfeghi, None; D.M. Moshfeghi, None; T. Hernandez-Boussard, None; R.A. Charalel, None; J.M. Morton, None.
  • Footnotes
    Support  The Palm Beach Community Trust Fund
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 6052. doi:
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      A. A. Moshfeghi, D. M. Moshfeghi, T. Hernandez-Boussard, R. A. Charalel, J. M. Morton; The Impact of Neonatal Endophthalmitis on Hospital Charges. Invest. Ophthalmol. Vis. Sci. 2010;51(13):6052.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To determine the magnitude of hospital charges associated with newborns who develop neonatal endophthalmitis compared with those who do not develop endophthalmitis in the United States between 1998-2006.

Methods: : We utilized the Nationwide Inpatient Sample database, a 20% representative sample of all hospital discharges in the United States, to help refine our understanding of the socioeconomic implications of this condition. In this retrospective cohort study, International Classification of Diseases-9 (ICD-9) codes for endophthalmitis in hospitalized infants and neonates were searched in the database and tracked over time.

Results: : Using the NIS, it was determined that between 1998 and 2006 there were 35.49 million live births in the United States. Among these, 1,959 cases of endophthalmitis were observed for a cumulative incidence of 5.52 cases per 100,000 live births per year. Patients with endophthalmitis had a mean total charge of $43,684 compared with $4,680 for patients who did not have endophthalmitis during their postnatal hospital admission (p < 0.0001).

Conclusions: : The significant difference in hospital charges is likely correlated with the fact that mean length of hospital stay for newborns with endophthalmitis (14.98 days) was significantly longer than those newborns without endophthalmitis (2.89 days, p < 0.001) in addition to the additional interventions and procedures that are required for this more complicated cohort of newborns. Clearly the development of endophthalmitis in the neonatal period places a significant financial strain on patient’s families, our hospitals, and the healthcare system as a whole. This is also borne out by the fact that newborns with endophthalmitis were significantly more likely to be born at a teaching hospital--where more prenatal cases with anticipated complications are typically referred--than those without endophthalmitis.

Keywords: clinical (human) or epidemiologic studies: health care delivery/economics/manpower • clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology • endophthalmitis 

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