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C. I. Tsika, G. A. Kontadakis, S. Plainis, M. I. Makridaki, M. K. Tsilimbaris; Blue Light Absorption of the Crystalline Lens and Tinted and Not Tinted Intraocular Lenses. Invest. Ophthalmol. Vis. Sci. 2008;49(13):410. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate psychophysically the absorption of blue light by the crystalline lens and by tinted and and non-tinted IOLs after cataract surgery.
The absorption of blue light was assessed in 29 patients (mean age 68, range 41-79) with variant density of nuclear senile cataract (0 to 3+), by measuring the parafoveal relative sensitivity of blue-green radiation using Heterochromatic Flicker Photometry (HFP) (MPS 9000 QuantifEYETM, ZeaVision©). 15 patients among them (mean age 66, range 41-78) underwent cataract or clear lens extraction. Tinted and not tinted IOL was implanted in a group of 6 patients (mean age 67, range 45-76) and 9 patients (mean age 65, range 41-78), respectively. At the 15th postoperative day HFP was repeated and the results were analyzed by non-parametric statistical tests.
A significant positive correlation was found between lens absorption and cataract density (r=0.5, p=0.006), at the pre-op group. At the follow-up measurements, there was a significant reduction in blue light absorption at the not tinted IOL group, compared to pre-op measurements (p=0.01), whereas at the tinted IOL group no significant difference was found (p=0.75). A significant difference in blue light absorption between the two different IOL groups (p=0.01) was also found postoperatively.
The human crystalline lens absorbs more at the blue spectrum with the progression of cataract density. The tinted IOLs appears to mimic the light-attenuating characteristics of the ageing & cataractous lens This may offer protection to the retina from the photochemical damage caused by high energy short wavelength radiation.
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