May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
A Comparison of the Antimicrobial Activity of Hydrophobic Acrylic versus Hydrophilic Collamer Intraocular Lenses Soaked in Moxifloxacin 0.5% for One Hour
Author Affiliations & Notes
  • H. Attia
    Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York
    Ophthalmology, Department of Veterans Affairs New York Harbor Healthcare System, Brooklyn, New York
  • A.-R. Elbash
    Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York
    Ophthalmology, Department of Veterans Affairs New York Harbor Healthcare System, Brooklyn, New York
  • D. R. Lazzaro
    Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York
  • P. D. Berg
    Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York
    Ophthalmology, Department of Veterans Affairs New York Harbor Healthcare System, Brooklyn, New York
  • A. Schrier
    Ophthalmology, Columbia-Presbyterian and Harkness Eye Institute,, New York, New York
  • E. F. Smith
    Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York
    Ophthalmology, Department of Veterans Affairs New York Harbor Healthcare System, Brooklyn, New York
  • I. Eid
    Ophthalmology, Department of Veterans Affairs New York Harbor Healthcare System, Brooklyn, New York
  • Footnotes
    Commercial Relationships  H. Attia, None; A. Elbash, None; D.R. Lazzaro, None; P.D. Berg, None; A. Schrier, None; E.F. Smith, None; I. Eid, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 411. doi:https://doi.org/
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      H. Attia, A.-R. Elbash, D. R. Lazzaro, P. D. Berg, A. Schrier, E. F. Smith, I. Eid; A Comparison of the Antimicrobial Activity of Hydrophobic Acrylic versus Hydrophilic Collamer Intraocular Lenses Soaked in Moxifloxacin 0.5% for One Hour. Invest. Ophthalmol. Vis. Sci. 2008;49(13):411. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To compare the antimicrobial activity of Alcon Acrysof SN60 acrylic hydrophobic intraocular lenses to the STARR Afinity CQ2015 Collamer hydrophilic intraocular lens after soaking in moxifloxacin 0.5% for one hour.

Methods: : Twenty (20) STARR Afinity CQ2015 Collamer intraocular lenses and twenty (20) Alcon Acrysof SN60 acrylic intraocular lenses were soaked in moxifloxacin 0.5% for one hour, then air dried for one minute on each side and plated on Mueller Hinton agar with quality controlled ATCC 25923 Staphylococcus aureus overlay.

Results: : All antibiotic soaked IOLs had kill zones. Average kill zones for the STARR Afinity hydrophilic collamer lens (40.2mm) was greater than for the Alcon SN60 hydrophobic acrylic lens (36.5mm). A comparison of condition means was performed using repeated measure ANOVA which was found to be highly significant P<0.001.

Conclusions: : Both acrylic and collamer antibiotic soaked lenses have antimicrobial activity. Hydrophilic collamer lenses have greater antimicrobial activity than hydrophobic acrylic IOLs after soaking in moxifloxacin 0.5% for one hour.

Keywords: intraocular lens • antibiotics/antifungals/antiparasitics • clinical laboratory testing 
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