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H. Attia, A.-R. Elbash, D. R. Lazzaro, P. D. Berg, A. Schrier, E. F. Smith, I. Eid; A Comparison of the Antimicrobial Activity of Hydrophobic Acrylic versus Hydrophilic Collamer Intraocular Lenses Soaked in Moxifloxacin 0.5% for One Hour. Invest. Ophthalmol. Vis. Sci. 2008;49(13):411. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the antimicrobial activity of Alcon Acrysof SN60 acrylic hydrophobic intraocular lenses to the STARR Afinity CQ2015 Collamer hydrophilic intraocular lens after soaking in moxifloxacin 0.5% for one hour.
Twenty (20) STARR Afinity CQ2015 Collamer intraocular lenses and twenty (20) Alcon Acrysof SN60 acrylic intraocular lenses were soaked in moxifloxacin 0.5% for one hour, then air dried for one minute on each side and plated on Mueller Hinton agar with quality controlled ATCC 25923 Staphylococcus aureus overlay.
All antibiotic soaked IOLs had kill zones. Average kill zones for the STARR Afinity hydrophilic collamer lens (40.2mm) was greater than for the Alcon SN60 hydrophobic acrylic lens (36.5mm). A comparison of condition means was performed using repeated measure ANOVA which was found to be highly significant P<0.001.
Both acrylic and collamer antibiotic soaked lenses have antimicrobial activity. Hydrophilic collamer lenses have greater antimicrobial activity than hydrophobic acrylic IOLs after soaking in moxifloxacin 0.5% for one hour.
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