May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Prevalence of Age-Related Macular Degeneration in the AGES - Reykjavik Study
Author Affiliations & Notes
  • F. Jonasson
    Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
    Faculty of Medicine, University of Iceland, Reykjavik, Iceland
  • A. Arnarsson
    University of Akureyri, Akureyri, Iceland
  • G. Eiriksdottir
    Icelandic Heart Association, Kopavogur, Iceland
  • T. Harris
    Laboratory of Epidemiology, Demography and Biometry, Intramural Research Program, National Institute on Ageing, Bethesda, Maryland
  • L. Launer
    Laboratory of Epidemiology, Demography and Biometry, Intramural Research Program, National Institute on Ageing, Bethesda, Maryland
  • B. E. K. Klein
    Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin
  • R. Klein
    Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin
  • M. F. Cotch
    Division of Epidemiology and Clinical Research, National Eye Institute, Bethesda, Maryland
  • V. Gudnason
    Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Icelandic Heart Association, Kopavogur, Iceland
  • Footnotes
    Commercial Relationships  F. Jonasson, None; A. Arnarsson, None; G. Eiriksdottir, None; T. Harris, None; L. Launer, None; B.E.K. Klein, None; R. Klein, None; M.F. Cotch, None; V. Gudnason, None.
  • Footnotes
    Support  N01-AG-12100 & NEI
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 594. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      F. Jonasson, A. Arnarsson, G. Eiriksdottir, T. Harris, L. Launer, B. E. K. Klein, R. Klein, M. F. Cotch, V. Gudnason; Prevalence of Age-Related Macular Degeneration in the AGES - Reykjavik Study. Invest. Ophthalmol. Vis. Sci. 2008;49(13):594. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To determine the prevalence and risk factors for age-related macular degeneration in the Age, Gene/Environment Susceptibility - Reykjavik Study (AGES - Reykjavik).

Methods: : The random sample includes individuals born between 1907 and 1935 who were recruited to participate in the AGES study between 2002-2006. Of the 7995 persons invited, 5764 participated in the 1st AGES-Reykjavik (72.1%) and of these 5272 participated in the 3rd follow-up visit which included an eye examination. After a maximum dilatation of the pupil all had a digital fundus photography centered on the macula. The photographs were graded by masked graders at the Wisconsin Ocular Epidemiology Grading Center using a modification of the Wisconsin Age-related Maculopathy Grading System.

Results: : The participants were 67 years and older. There were 5138 right macular fundus photographs gradable for early age-related maculopathy (ARM). The prevalence of early ARM was 18.3% (95% CI 17.3-18.9). Among the participants 4.4% (95% CI 3.9-4.7) had late age-related macular degeneration (AMD). For pure geographic atrophy (GA) there were 5036 gradable photographs of the right macula and the prevalence was 2.1% (95% CI 1.7-2.3). Those with GA and also exudative AMD (mixed type) are not included in this category. For exudative late AMD there were 5152 gradable photographs of the right macula and the prevalence was 2.3% (95% CI 1.9-2.5). The Geographic atrophy when present was located in the centre circle (foveal area) in the vast majority of cases.

Keywords: age-related macular degeneration • clinical (human) or epidemiologic studies: prevalence/incidence • macula/fovea 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×