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V. Tompkin, K. Mandal, A. C. Fisher, A. P. Tompkin, S. Murjaneh, N. Collaer, P. M. Lenfestey, I. A. Pearce, M. C. Briggs, S. P. Harding; Variation in Measures of Visual Function in Patients With Neovascular Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2008;49(13):601.
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© ARVO (1962-2015); The Authors (2016-present)
To determine the variability in three different measurements of vision (distance DV, near NV, contrast sensitivity CS) in patients presenting with neovascular macular degeneration (nMD) and compared with age.
Patients presenting with nMD were recruited in a regional centre. Refraction protocol best-corrected DV, NV and CS were measured by accredited testers using 2m logMAR, 25cm logMAR and 1m Pelli-Robson charts respectively using standardised illumination. The visual parameters (DV, NV, CS) of the index eye were analyzed versus age.
Patients were recruited between November 1999 to October 2006. 900 eyes had DV and CS recorded; a subset of which (437) had NV documented. Median DV, NV and CS were 47 letters, 1.00 logMAR and 23 letters respectively. 25th to 75th percentile for DV was 37-58 letters, for NV was 0.7-1.3 logMAR and for CS was 18-27 letters.| r | = 0.15 (p<0.01) for DV, | r | =0.10 (p<0.05) for NV and | r | = 0.18 (p<0.01) for CS. Regression analysis showed a highly significant weak negative correlation of all three visual parameters versus age at presentation, i.e. DV, NV and CS.
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