May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Variation in Measures of Visual Function in Patients With Neovascular Macular Degeneration
Author Affiliations & Notes
  • V. Tompkin
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • K. Mandal
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • A. C. Fisher
    Department of Clinical Engineering, University of Liverpool, Liverpool, United Kingdom
  • A. P. Tompkin
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • S. Murjaneh
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • N. Collaer
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • P. M. Lenfestey
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • I. A. Pearce
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • M. C. Briggs
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • S. P. Harding
    Clinical Eye Research Centre, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom
  • Footnotes
    Commercial Relationships  V. Tompkin, None; K. Mandal, None; A.C. Fisher, None; A.P. Tompkin, None; S. Murjaneh, None; N. Collaer, None; P.M. Lenfestey, None; I.A. Pearce, None; M.C. Briggs, None; S.P. Harding, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 601. doi:https://doi.org/
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      V. Tompkin, K. Mandal, A. C. Fisher, A. P. Tompkin, S. Murjaneh, N. Collaer, P. M. Lenfestey, I. A. Pearce, M. C. Briggs, S. P. Harding; Variation in Measures of Visual Function in Patients With Neovascular Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2008;49(13):601. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine the variability in three different measurements of vision (distance DV, near NV, contrast sensitivity CS) in patients presenting with neovascular macular degeneration (nMD) and compared with age.

Methods: : Patients presenting with nMD were recruited in a regional centre. Refraction protocol best-corrected DV, NV and CS were measured by accredited testers using 2m logMAR, 25cm logMAR and 1m Pelli-Robson charts respectively using standardised illumination. The visual parameters (DV, NV, CS) of the index eye were analyzed versus age.

Results: : Patients were recruited between November 1999 to October 2006. 900 eyes had DV and CS recorded; a subset of which (437) had NV documented. Median DV, NV and CS were 47 letters, 1.00 logMAR and 23 letters respectively. 25th to 75th percentile for DV was 37-58 letters, for NV was 0.7-1.3 logMAR and for CS was 18-27 letters.| r | = 0.15 (p<0.01) for DV, | r | =0.10 (p<0.05) for NV and | r | = 0.18 (p<0.01) for CS. Regression analysis showed a highly significant weak negative correlation of all three visual parameters versus age at presentation, i.e. DV, NV and CS.

Keywords: age-related macular degeneration • visual acuity • contrast sensitivity 
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