May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Characterization of Higher Order Aberrations in Eyes With Dohlman/Boston Keratoprostheses and Comparison With Penetrating Keratoplasty and Normal Eyes
Author Affiliations & Notes
  • K. Stasi
    Dept of Ophthalmology, Rochester Eye Institute, Rochester, New York
  • S. Pantanell
    Center for Visual Sciences, University of Rochester, New York
  • R. Sabesan
    Center for Visual Sciences, University of Rochester, New York
  • G. Yoon
    Center for Visual Sciences, University of Rochester, New York
  • G. McCormick
    Dept of Ophthalmology, Rochester Eye Institute, Rochester, New York
  • J. V. Aquavella
    Dept of Ophthalmology, Rochester Eye Institute, Rochester, New York
  • Footnotes
    Commercial Relationships  K. Stasi, None; S. Pantanell, None; R. Sabesan, None; G. Yoon, None; G. McCormick, None; J.V. Aquavella, None.
  • Footnotes
    Support  Research to Prevent Blindness
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1038. doi:
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      K. Stasi, S. Pantanell, R. Sabesan, G. Yoon, G. McCormick, J. V. Aquavella; Characterization of Higher Order Aberrations in Eyes With Dohlman/Boston Keratoprostheses and Comparison With Penetrating Keratoplasty and Normal Eyes. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1038.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the optical quality of the Dohlman/Boston keratoprosthesis (Kpro) implanted in patients by measuring higher order aberrations and to compare them to eyes after penetrating keratoplasty (PK) and to normal eyes.

Methods: : A Shack-Hartmann wavefront sensor was used to measure higher order aberrations in five patients with the Kpro implanted with and without the bandage contact lens (BCL). Wavefront aberration data on 378 normal eyes (pre-LASIK) and 14 eyes after PK were adjusted for a 3mm pupil in order to compare to the Kpro with 3mm optical zone data. The outcome measures used for comparison included Zernike modes up to the 5th order and higher order root mean square (HORMS) wavefront error.

Results: : Kpro patients had uncorrected visual acuity between 20/30 and 20/100. The most prevelant Higher Order Aberrations (HOAs) in Kpro patients were trefoil, coma and quadrafoil, both in patients with and without the bandage contact lens (BCL). Kpro patients had a HORMS of 0.30+0.16 and 0.36+0.18 µm with and without the BCL, respectively (standard deviation values in parenthesis). Post-PK eyes had uncorrected visual acuity between 20/30 and 20/200. The most prevalent HOAs in post-PK patients were coma, trefoil, secondary astigmatism and spherical aberration. Post-PK patients showed HORMS of 2.25+0.98 µm for 6mm pupil. After the measurements were adjusted for 3mm pupil, HORMS was 0.28+0.13 µm in post-PK patients. Normal pre-LASIK eyes with uncorrected visual acuity between 20/30 and 20/100 had a HORMS of 0.05+0.02 µm adjusted for 3mm pupil. Second order RMS was 0.83+0.93, 0.47+0.46, 1.10+0.26 and 1.05+0.49 for the Kpro with BCL, Kpro without BCL, PK and normal pre-LASIK eyes, respectively. The Kpro eyes had less 2nd order aberrations than PK and normal pre-LASIK eyes by the equivalent of approximately 1.6 Diopters of sphere.

Conclusions: : Higher order aberrations of the Dohlman/Boston keratoprosthesis Type I were clinically similar to that of eyes after PK when adjusted for 3mm pupil, but significantly less when compared to the PK data for 6mm pupil. The Kpro eyes showed significantly smaller residual refractive errors compared to the PK eyes.

Keywords: keratoprostheses • aberrations 
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