May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
A New Provocative Test for Glaucoma?
Author Affiliations & Notes
  • F. N. Kanadani
    Santa Casa of Belo Horizonte, Belo Horizonte, Brazil
    Ophthalmology/Glaucoma,
  • T. C. A. Moreira
    Santa Casa of Belo Horizonte, Belo Horizonte, Brazil
    Ophthalmology,
  • F. H. Melo
    Santa Casa of Belo Horizonte, Belo Horizonte, Brazil
    Ophthalmology/Glaucoma,
  • A. C. Nery
    Santa Casa of Belo Horizonte, Belo Horizonte, Brazil
    Ophthalmology/Glaucoma,
  • J. N. Dias
    Santa Casa of Belo Horizonte, Belo Horizonte, Brazil
    Ophthalmology/Glaucoma,
  • V. C. Barbosa
    Santa Casa of Belo Horizonte, Belo Horizonte, Brazil
    Ophthalmology/Glaucoma,
  • S. K. Dorairaj
    Ophthalmology/Glaucoma, Einhorn Research Center, New York Eye and Ear Infirmary, New York
    Beth Israel Medical Center, New York, New York
  • J. A. Netto
    Santa Casa of Belo Horizonte, Belo Horizonte, Brazil
    Ophthalmology,
  • Footnotes
    Commercial Relationships  F.N. Kanadani, None; T.C.A. Moreira, None; F.H. Melo, None; A.C. Nery, None; J.N. Dias, None; V.C. Barbosa, None; S.K. Dorairaj, None; J.A. Netto, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1059. doi:
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      F. N. Kanadani, T. C. A. Moreira, F. H. Melo, A. C. Nery, J. N. Dias, V. C. Barbosa, S. K. Dorairaj, J. A. Netto; A New Provocative Test for Glaucoma?. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1059.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To compare the water-drinking test with the 30-degree inverted body position test on intraocular pressure (IOP) in normal, suspects, and glaucoma patients.

Methods: : Based on clinical evaluation of the optic disc, IOP, and standard achromatic perimetry (SAP) of 71 eyes, 18 were "normal" (normal SAP and optic disc evaluation, and IOP < 21 mmHg), 30 were "glaucoma suspect" (GS; normal SAP, C/D ratio > 0.5 or asymmetry > 0.2 and/or ocular hypertension), and 31 had "early glaucoma" (MD < -6 dB, glaucomatous optic neuropathy). SAP was performed with the Octopus 3.1.1 Dynamic 24-2 program. Patients fasted before water drinking test, and four measurements were performed at basal, 15', 30' and 45' after drinking 1 liter of water (WDT) in 5 minutes. In the 30-degree inverted position, IOP measurement with Perkins applanation tonometer was taken after five minutes lying down.

Results: : There was a statistical difference in all groups between the basal IOP and peak IOP during the WDT (p<0,001) and in the inverted position IOP (p<0,001). There were no difference among controls (p=0,50), suspects (p=0,41) and glaucoma patients (p=1,0) between WDT IOP and inverted position IOP.

Conclusions: : The 30-degree inverted position test was as good as WDT in detecting peak IOP. This new provocative test is easier, faster and more comfortable for both patients and doctors.

Keywords: intraocular pressure • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials 
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