Abstract
Purpose: :
This study was conducted to verify if there is a relationship between the WDT results and the body mass index of the patients submitted to this test.
Methods: :
Prospective analysis of 63 randomly selected eyes of 63 OH or OAG patients. All patients were submitted to a modified diurnal tension curve (IOP measurements taken at 8:00AM, 10:30AM, 14:00AM and 16:00PM) followed by the WDT. WDT basal IOP was considered as the mean ±SD IOP at 16:00PM. Diurnal fluctuation was considered the difference between the highest IOP level detected by the WDT minus the lowest IOP value detected by the modified diurnal tension curve. BMI was calculated as weight/height2. The relationships between BMI and diurnal fluctuation and BMI and WDT peak were assessed. For the statistical analysis, paired t test and Pearson's correlation analysis were used.
Results: :
63 patients were evaluated. Mean +SD weight was 68.79+10.87 (45-113) kg. Mean +SD height was 161.56+9.45 (140-187) cm. Mean±SD BMI value was 26.42±4.02 (20.15 - 36.22). Mean basal ±SD IOP was 24.0±3.8 mmHg. After water ingestion, mean ±SD IOP peak was 29.3±4.9 mmHg (p<0.001), with a mean diurnal fluctuation of 5.3+2.4 mmHg. In the analysis of BMI vs WDT peak and BMI vs Diurnal fluctuation, R2 values were 0.097 (p=0.01) and 0.003 (p=0.65).
Conclusions: :
In this study, no relationship between BMI and WDT results was found.
Keywords: intraocular pressure • outflow: trabecular meshwork • stress response