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G. L. Spaeth, Y. Wang, D. S. M. d. Barros, J. B. V. K. Navarro, S. J. Fudemberg, S. Wizov; Asymmetric Intraocular Pressure in Subjects With or Without Glaucoma. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1064.
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To determine whether intraocular pressure (IOP) asymmetry between fellow eyes may be used to help diagnose the presence of open - angle glaucoma (OAG).
One hundred and ninety eight subjects were analyzed, including 100 normal subjects and 98 subjects with open - angle glaucoma. Different levels of IOP asymmetry were assessed for their association with OAG.
IOP asymmetry (the absolute value of right minus left eye) in subjects with OAG was statistically significant from those without OAG (P = 0.01, OR 2.0). No glaucoma patient had complete IOP symmetry, whereas 34% of normals had the same IOP in both eyes. (P=0.000, Χ2= 42.132). 17 cases of glaucoma (17%) had an asymmetry of IOP greater than 6mmHg, however, no normal subject had that amount (P=0.000, Fisher’s exact test, Χ2= 16.83).
Intraocular pressure asymmetry, especially when absent or marked, can help to rule in or rule out the diagnosis of open - angle glaucoma (OAG).
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