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M. Ng, L. Racette, J. M. Liebmann, C. A. Girkin, S. L. Lovell, L. M. Zangwill, R. N. Weinreb, P. A. Sample; A Comparison of Short-Wavelength Automated Perimetry Using the Swedish Interactive Threshold Algorithm (SWAP-SITA) to the Full-Threshold method (SWAP-FT) and Standard Automated Perimetry (SAP-SITA). Invest. Ophthalmol. Vis. Sci. 2008;49(13):1073.
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© ARVO (1962-2015); The Authors (2016-present)
To assess how well SWAP-SITA, SWAP-FT and SAP-SITA outcomes match optic disc stereophotograph classifications of glaucoma, and to evaluate agreement across the visual function tests.
One eye of 306 glaucoma patients and 307 age-matched healthy participants from the Diagnostic Innovations in Glaucoma Study (DIGS) were included. Masked grading of optic disc stereophotographs classified the eyes as glaucomatous or normal. Stereophotographs were taken within 6 mos of the visual function tests, which were conducted within 3mos. For descriptive purposes, SAP-SITA mean deviation ±SD and pattern standard deviation was -4.40 ±6.26 and -1.00 ±1.89, and 4.33 ±3.72 and 2.06 ±1.05 for glaucomatous and normal eyes, respectively. Several parameters were assessed for each test; reported here are pattern standard deviation (PSD) and the number of pattern deviation points (PDP) triggered at <1%. Receiver operating characteristic curves were generated and the area under the curves (AUC) computed. Sensitivity at 80% and 90% specificity was calculated and agreement between visual function tests was evaluated using Kappa statistics (k).
AUCs ranged from 0.695 ±0.020 - 0.721 ±0.020 and were not significantly different across all tests (p > 0.05). Sensitivity at 80% and 90% specificity ranged from 52.9% - 55.6% and 38.2% - 45.4%, respectively. At 80% specificity, there was substantial agreement between SWAP-SITA and SWAP-FT PSD,k=0.619, and moderate agreement between all other comparisons, k=0.517 - 0.583. At 90% specificity, there was moderate agreement between SWAP-SITA and SWAP-FT PDP, k=0.601, and substantial agreement between all other comparisons, k=0.619 - 0.703.
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