May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
A Comparison of Short-Wavelength Automated Perimetry Using the Swedish Interactive Threshold Algorithm (SWAP-SITA) to the Full-Threshold method (SWAP-FT) and Standard Automated Perimetry (SAP-SITA)
Author Affiliations & Notes
  • M. Ng
    Ophthalmology, Hamilton Glaucoma Center, La Jolla, California
  • L. Racette
    Ophthalmology, Hamilton Glaucoma Center, La Jolla, California
  • J. M. Liebmann
    New York Eye and Ear Infirmary, New York, New York
  • C. A. Girkin
    Ophthalmology, University of Alabama, Birmingham, Alabama
  • S. L. Lovell
    Ophthalmology, Hamilton Glaucoma Center, La Jolla, California
  • L. M. Zangwill
    Ophthalmology, Hamilton Glaucoma Center, La Jolla, California
  • R. N. Weinreb
    Ophthalmology, Hamilton Glaucoma Center, La Jolla, California
  • P. A. Sample
    Ophthalmology, Hamilton Glaucoma Center, La Jolla, California
  • Footnotes
    Commercial Relationships  M. Ng, None; L. Racette, None; J.M. Liebmann, Carl Zeiss Meditec, F; C.A. Girkin, Carl Zeiss Meditec, F; Heidelberg Engineering, F; Optovue, F; Merck, F; S.L. Lovell, None; L.M. Zangwill, Heidelberg Engineering, F; Carl Zeiss Meditech, F; Optovue, F; Allergan, F; R.N. Weinreb, Heidelberg Engineering, F; Carl Zeiss Meditech, F; Alcon, C; Allergan, C; Pfizer, C; Carl Zeiss Meditech, C; Heidelberg Engineering, R; Carl Zeiss Meditech, R; P.A. Sample, Carl Zeiss Meditech, F; Welch Allyn, F; Haag Streit, F.
  • Footnotes
    Support  EY U1014267, EY14267 (PAS), EY08208 (PAS), EY11008 (LMZ), EY13959 (CAG), Eyesight Foundation of AL (CAG); grants in the form of glaucoma medication at no cost: Alcon, Allergan, Pfizer, SANTEN, Merck.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1073. doi:https://doi.org/
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      M. Ng, L. Racette, J. M. Liebmann, C. A. Girkin, S. L. Lovell, L. M. Zangwill, R. N. Weinreb, P. A. Sample; A Comparison of Short-Wavelength Automated Perimetry Using the Swedish Interactive Threshold Algorithm (SWAP-SITA) to the Full-Threshold method (SWAP-FT) and Standard Automated Perimetry (SAP-SITA). Invest. Ophthalmol. Vis. Sci. 2008;49(13):1073. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To assess how well SWAP-SITA, SWAP-FT and SAP-SITA outcomes match optic disc stereophotograph classifications of glaucoma, and to evaluate agreement across the visual function tests.

Methods: : One eye of 306 glaucoma patients and 307 age-matched healthy participants from the Diagnostic Innovations in Glaucoma Study (DIGS) were included. Masked grading of optic disc stereophotographs classified the eyes as glaucomatous or normal. Stereophotographs were taken within 6 mos of the visual function tests, which were conducted within 3mos. For descriptive purposes, SAP-SITA mean deviation ±SD and pattern standard deviation was -4.40 ±6.26 and -1.00 ±1.89, and 4.33 ±3.72 and 2.06 ±1.05 for glaucomatous and normal eyes, respectively. Several parameters were assessed for each test; reported here are pattern standard deviation (PSD) and the number of pattern deviation points (PDP) triggered at <1%. Receiver operating characteristic curves were generated and the area under the curves (AUC) computed. Sensitivity at 80% and 90% specificity was calculated and agreement between visual function tests was evaluated using Kappa statistics (k).

Results: : AUCs ranged from 0.695 ±0.020 - 0.721 ±0.020 and were not significantly different across all tests (p > 0.05). Sensitivity at 80% and 90% specificity ranged from 52.9% - 55.6% and 38.2% - 45.4%, respectively. At 80% specificity, there was substantial agreement between SWAP-SITA and SWAP-FT PSD,k=0.619, and moderate agreement between all other comparisons, k=0.517 - 0.583. At 90% specificity, there was moderate agreement between SWAP-SITA and SWAP-FT PDP, k=0.601, and substantial agreement between all other comparisons, k=0.619 - 0.703.

Keywords: visual fields 
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