May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
A Cumulative Defect (Bebie') Curve for the Humphrey Matrix Frequency Doubling Technology (FDT) Perimeter
Author Affiliations & Notes
  • C. A. Johnson
    Ophthal-Discoveries in Sight, Devers Eye Institute, Portland, Oregon
  • M. Wall
    Ophthalmology and Neurology, Univ of Iowa, Iowa City, Iowa
  • M. Zeppieri
    Ophthalmology, S. Maria della Misericordia Hospital, Udine, Italy
  • P. Brusini
    Ophthalmology, S. Maria della Misericordia Hospital, Udine, Italy
  • Footnotes
    Commercial Relationships  C.A. Johnson, Welch Allyn, F; Welch Allyn, C; M. Wall, None; M. Zeppieri, None; P. Brusini, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1077. doi:https://doi.org/
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      C. A. Johnson, M. Wall, M. Zeppieri, P. Brusini; A Cumulative Defect (Bebie') Curve for the Humphrey Matrix Frequency Doubling Technology (FDT) Perimeter. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1077. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To develop cumulative defect (Bebie’) curves for the Humphrey Matrix Frequency Doubling Technology (FDT) perimeter and evaluate its clinical utility for glaucoma, retina and neuro-ophthalmology patients.

 
Methods:
 

Data from testing both eyes of 261 normal controls subjects (ages 18 to 88) on the Humphrey Matrix using the 24-2 central visual field test procedure were used to generate cumulative defect Bebie’ curves. Normal subjects were required to have a normal eye examination, no history of ocular surgery other than uncomplicated cataract surgery, best corrected visual acuity of 20/40 or better, IOP less than 21 mm Hg, no systemic diseases, normal standard automated perimetry visual fields, refractive errors less than 5 D sphere and 2 D cylinder, and no medications known to affect visual field sensitivity. To adjust for normal sensitivity aging changes, all data was transformed to a 45 year old sensitivity equivalent. Cumulative defect curves were generated by ranking individual sensitivity values (55 locations) from highest to lowest.

 
Results:
 

The Humphrey Matrix 24-2 normal cumulative defect curve for normal right eyes (mean and 95% confidence limits) is presented in the figure below. Examples of diffuse, localized and combined visual field deficits will be presented for glaucoma, retinal disease, neuro-ophthalmologic conditions and artifactual test results. The Humphrey Matrix 24-2 normal cumulative defect curve for normal right eyes (mean and 95% confidence limits) is presented in the figure to the right. Examples of diffuse, localized and combined visual field deficits will be presented for glaucoma, retinal disease, neuro-ophthalmologic conditions and artifactual test results.

 
Conclusions:
 

The cumulative defect curve for the Humphrey Matrix represents a clinical data representation procedure that permits generalized (diffuse) and localized visual field losses for ocular and neurologic disorders.  

 
Keywords: perimetry • visual fields • clinical research methodology 
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