May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Long-Term Perimetric Variability in Patients With Different Stages of Glaucoma
Author Affiliations & Notes
  • S. Romano
    Eye Clinic, Department of Medicine, Surgery and Odontoiatry, San Paolo Hospital, University of Milan, Milan, Italy
  • P. Fogagnolo
    G.B. Bietti Foudation – IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Rome, Italy
  • S. Ranno
    Eye Clinic, Department of Medicine, Surgery and Odontoiatry, San Paolo Hospital, University of Milan, Milan, Italy
  • L. Rossetti
    Eye Clinic, Department of Medicine, Surgery and Odontoiatry, San Paolo Hospital, University of Milan, Milan, Italy
  • M. Figus
    Eye Clinic, University of Pisa, Pisa, Italy
  • A. Ferreras
    Miguel Servet University Hospital, Zaragoza, Spain
  • F. Oddone
    G.B. Bietti Foudation – IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Rome, Italy
  • N. Orzalesi
    Eye Clinic, Department of Medicine, Surgery and Odontoiatry, San Paolo Hospital, University of Milan, Milan, Italy
  • Footnotes
    Commercial Relationships  S. Romano, None; P. Fogagnolo, None; S. Ranno, None; L. Rossetti, None; M. Figus, None; A. Ferreras, None; F. Oddone, None; N. Orzalesi, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1088. doi:https://doi.org/
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    • Get Citation

      S. Romano, P. Fogagnolo, S. Ranno, L. Rossetti, M. Figus, A. Ferreras, F. Oddone, N. Orzalesi; Long-Term Perimetric Variability in Patients With Different Stages of Glaucoma. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1088. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To provide mean values and 95% confidence intervals (CI) for perimetric long-term variability (LTV) of glaucomatous patients with different stages of the disease.

 
Methods:
 

We reviewed the perimetric data of 49 glaucoma patients (age, F/M) who underwent a mean of 4 visual fields (Humphrey 30-2, white-on-white program) over a follow-up of 24 months. All patients were clinically stable (during the study, no changes occurred in: medical regimen, perimetric indices and clusters of abnormal points, optic nerve head appearance and mean intraocular pressure). The stage of the disease was classified according to the Glaucoma Staging System 2 (GSS2). LTV was calculated as the mean of the square roots of the point-to-point variances throughout repetitions. For each stage, mean LTV, standard deviation, and confidence intervals were given.

 
Results:
 

The main results of the study are summarized in the Table. Patients at stage 0 had lower LTF compared to the other stages (P<0.05), while LTF was significantly higher in stage 4 compared to all the other stages (P<0.01).

 
Conclusions:
 

LTF significantly varied between stages of the disease at GGS2; a trough in fluctuation was found at stage 0, while it peaked at stage 4.  

 
Keywords: visual fields 
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