May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Correlation of Manually Determined Optic Cup and Disc Borders in Fundus Photographs With Anatomical Optic Nerve Head Structures in SDOCT Images
Author Affiliations & Notes
  • W. Sun
    Physics Department, Boston Univ., Boston, Massachusetts
    Wellman Ctr for Photomed., Mass General Hospital, Boston, Massachusetts
  • M. Mujat
    Wellman Ctr for Photomed., Mass General Hospital, Boston, Massachusetts
    Physical Sciences Inc., Andover, Massachusetts
  • T. C. Chen
    Glaucoma Service, Mass Eye and Ear Infirmary, Boston, Massachusetts
    Harvard Medical School, Boston, Massachusetts
  • K. Yi
    Glaucoma Service, Mass Eye and Ear Infirmary, Boston, Massachusetts
    Harvard Medical School, Boston, Massachusetts
  • G. Maguluri
    Wellman Ctr for Photomed., Mass General Hospital, Boston, Massachusetts
    Thorlabs Inc., Newton, New Jersey
  • B. H. Park
    Wellman Ctr for Photomed., Mass General Hospital, Boston, Massachusetts
    Harvard Medical School, Boston, Massachusetts
  • D. Ferguson
    Physical Sciences Inc., Andover, Massachusetts
  • D. Hammer
    Physical Sciences Inc., Andover, Massachusetts
  • N. Iftimia
    Physical Sciences Inc., Andover, Massachusetts
  • J. F. de Boer
    Wellman Ctr for Photomed., Mass General Hospital, Boston, Massachusetts
    Harvard Medical School, Boston, Massachusetts
  • Footnotes
    Commercial Relationships  W. Sun, None; M. Mujat, MGH, P; T.C. Chen, None; K. Yi, None; G. Maguluri, None; B.H. Park, MGH, P; D. Ferguson, PSI, P; D. Hammer, PSI, P; N. Iftimia, PSI, P; J.F. de Boer, NIDEK, F; MGH, P.
  • Footnotes
    Support  NIH Grant R01EY014975-01
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1179. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      W. Sun, M. Mujat, T. C. Chen, K. Yi, G. Maguluri, B. H. Park, D. Ferguson, D. Hammer, N. Iftimia, J. F. de Boer; Correlation of Manually Determined Optic Cup and Disc Borders in Fundus Photographs With Anatomical Optic Nerve Head Structures in SDOCT Images. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1179. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

To correlate the optic cup and disc determined from fundus photos with the anatomical structures visualized by spectral domain optical coherence tomography (SDOCT).

 
Methods:
 

The fundus photos of eleven eyes were correlated with the cross-sectional structures collected by our clinical video-rate SDOCT instrument by registering the fundus photos to the corresponding integrated reflectance (en-face) SDOCT maps. The optic cup and disc borders were drawn by two ophthalmologists on the fundus photos using a tablet PC. The location of the drawn borders in the cross-sectional SDOCT images were determined by axial projection.

 
Results:
 

Three eyes showed good agreement between subjective determinations of optic disc borders and the edges of the retinal pigment epithelium (RPE) (Fig. 1, top row), four showed moderate and four showed poor agreement (Fig. 1, bottom row). Fig. 1. Left column: fundus photos, black circles: manual drawings of the cup (inner circle) and disc (outer circle), green rectangle: OCT scan area. Middle column: SDOCT en-face images, blue circles: manual drawings superposed onto the SDOCT en-face images, red vertical line: position of the vertical cross-sectional SDOCT frame on the right. Right column: vertical cross-sectional SDOCT frames through the optic nerve head, red vertical lines: projections of the manual drawings (i.e. inner pair: estimated optic cup; outer pair: estimated optic disc).  

 
Conclusions:
 

The optic disc determined based on the color contrast in fundus photos does not necessarily correspond to the edges of the RPE; the optic cup correspondence remains unclear. A method based on anatomical retinal structures as clearly visualized by SDOCT might improve objectivity of cup and disc assessment.

 
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • optic disc • image processing 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×