May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
Thickness of the Nerve Fiber Layer in Optic Disc Edema Is Associated With Density of Visual Field Deficits
Author Affiliations & Notes
  • A. D. Meleth
    Ophthalmology, George Washington University, Washington, Dist. of Columbia
  • H. N. Sen
    Ophthalmology, George Washington University, Washington, Dist. of Columbia
  • Y. Mahmood
    Ophthalmology, George Washington University, Washington, Dist. of Columbia
  • C. E. Geist
    Ophthalmology, George Washington University, Washington, Dist. of Columbia
  • Footnotes
    Commercial Relationships  A.D. Meleth, None; H.N. Sen, None; Y. Mahmood, None; C.E. Geist, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 1185. doi:https://doi.org/
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      A. D. Meleth, H. N. Sen, Y. Mahmood, C. E. Geist; Thickness of the Nerve Fiber Layer in Optic Disc Edema Is Associated With Density of Visual Field Deficits. Invest. Ophthalmol. Vis. Sci. 2008;49(13):1185. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine the correlation of optic disc edema with thickness on ocular coherence tomography imaging and density of visual field deficit on Humphrey visual field testing.

Methods: : Retrospective chart review of patients seen in the George Washington University Ophthalmology clinic with a diagnosis of optic disc edema with concurrent OCT and HVF 30-2 over a 3 year period was performed. Variables examined included: underlying diagnosis, visual acuity, average nerve fiber layer thickness as measured by the fast nerve fiber layer thickness protocol for the Zeiss OCT, nerve fiber layer thickness by quadrant, reliability of visual field, mean deviation, pattern standard deviation, colour vision, presence or absence of afferent pupillary defect, cup/disc ratio, presence or absence of pallor, degree of edema, and presence or absence of spontaneous venous pulsations.

Results: : 9 eyes of 5 patients were included. The degree of optic disc edema on clinical exam correlated with thickening of the nerve fiber layer on OCT. In addition, preliminary data indicates that the degree of thickening on exam showed a modest correlation with the mean deviation on HVF 30-2 (r=0.61). Underlying diagnoses included idiopathic intracranial hypertension, HIV neuropathy, and optic neuritis.

Keywords: imaging/image analysis: clinical • perimetry • neuro-ophthalmology: optic nerve 
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