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M. N. Welch, D. E. E. Holck, M. C. Kavanagh, M. P. Ohr, C. N. Czyz, K. V. Cahill, J. A. Foster; Comparison of Fibrin Sealant vs. Suture for Wound Closure in Müller Muscle-Conjunctival Resection Repair. Invest. Ophthalmol. Vis. Sci. 2008;49(13):638.
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Comparison of fibrin sealant vs. suture for wound closure in Müller muscle-conjunctival resection ptosis repair.
The charts of 114 patients who had undergone Müller muscle-conjunctival resection were retrospectively reviewed. 211 eyelids were divided into two groups. Group 1 used suture for wound closure. Group 2 used fibrin sealant for wound closure. The preoperative and postoperative values were statistically compared using a paired t test. Complications were statistically analyzed using a two-tailed Fisher test. Postoperative symmetry (within 0.5 mm) and complications were compared.
Müller muscle-conjunctival resection ptosis repair was performed on 211 eyelids of 114 patients. Suture was used for wound closure on 45 eyelids (31 patients) and fibrin sealant was used on 166 eyelids (83 patients). The two groups did not differ statistically in lid height values. Postoperative symmetry within 0.5 mm was achieved in 28 of 31 patients (90%) in the sutured group and in 79 of 83 (95%) in the fibrin sealant group. In the suture group, eight of 31 patients (26%) had postoperative complications including moderate to severe pain (10%), suture granuloma (6%), corneal abrasion (3%), loose suture (3%), and persistent punctuate keratopathy (3%). No evidence of keratopathy or other complications were attributable to the fibrin sealant.
Müller muscle-conjunctival resection ptosis repair using fibrin sealant for wound closure offers comparable lid position results as compared to wound closure using traditional suture technique. Use of fibrin sealant showed fewer postoperative complications and was associated with a lower rate of subsequent surgical procedures.
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