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B. Wanichwecharungruang, V. Laopoolsuk, S. Sopitanont; Central Corneal Thickness in the Fellow Eye of Central Retinal Vein Occlusion Patients. Invest. Ophthalmol. Vis. Sci. 2008;49(13):654. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the central corneal thickness (CCT) in the fellow eyes of central retinal vein occlusion (FE-CRVO) patients
Ninety seven eyes of 97 FE-CRVO, and 112 eyes of 112 healthy controls were enrolled. Three measurements of CCT were obtained with ultrasound pachometry (Sonogage, Cleveland, OH). Patient who had corneal disease, and history of intraocular surgery, except 6-month post-operatively uncomplicated phacoemulsification, were excluded.
Mean age between FE-CRVO and controls was not different (59.6 and 54.9 years, respectively, P = 0.60). Males were more common in FE-CRVO than controls (47.4 % vs. 25%, P = 0.001). In FE-CRVO group, systemic status revealed diabetes (33 %), hypertension (58.8 %), dyslipidemia (16.5 %), ischemic heart (4.1%), aspirin taking (9.3 %), and smoking (6.2%). Glaucoma was detected in 21 eyes (21%) of FE-CRVO. Mean CCT of FE-CRVO was thinner than controls (529.2 vs. 543.3 microns, P = 0.001), (Table). Multivariate analysis revealed that age, sex, glaucoma, and systemic status, except aspirin taking, did not affect mean CCT.Table: Mean central corneal thickness between fellow eye of central retinal vein occlusion and control
Fellow eye of central retinal vein occlusion patients have thinner CCT than controls. Mean difference is 14 microns. Previous report demonstrates that CCT is not significantly different between eyes, thin CCT in FE-CRVO may be an independent risk factor of CRVO. The pathophysiology of this association is unclear, but may relate to weaker lamina cribosa in the thin CCT eye. In addition, the study of CCT in new cases of CRVO is ongoing in our institute.
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