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W. Huang, Z. Yan-fa, Q. Xia, M. He; The Relationship Between Central Corneal Thickness and Intraocular Pressure in Normal Subjects: The Liwan Eye Study. Invest. Ophthalmol. Vis. Sci. 2008;49(13):693. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the effects of central corneal thickness (CCT) on intraocular pressure (IOP) measurement, and the associations with age and gender.
Adults aged 50 years and over were selected using cluster random sampling in Liwan District, Guangzhou. CCT was measured using ultrasound pachymetry, and IOP using Tono-Pen applanation tonometer. The data were presented only for normal subjects.
The mean IOP was 15.18±3.04mmHg, 15.06±3.06mmHg in right and left eyes, respectively. CCT was 541.34±32.69µm,542.35±31.24µm in right and left eyes, respectively. Negative correlation with age was observed for both IOP (r=-0.077, P=0.006 in right eyes; r=-0.065, P=0.020 in left eyes) and CCT (r=-0.129, P=0.000 in right eyes; r=-0.121, P=0.000 in left eyes). However, there was positive correlation with CCT and IOP(r=0.225, P=0.000 in right eyes; r=0.216, P=0.000 in left eyes). The IOP increased by 1.9mmHg for every 100µm increase of CCT in right eyes. This value was 2.0mmHg/100µm. IOP measurement deviated by 1.03 mmHg and 1.08 mmHg as per 10% CCT change in right and left eyes.
Older people appear to have a lower IOP and thinner CCT. IOP measurement was highly associated with CCT.
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