Abstract
Purpose: :
To assess the effects of central corneal thickness (CCT) on intraocular pressure (IOP) measurement, and the associations with age and gender.
Methods: :
Adults aged 50 years and over were selected using cluster random sampling in Liwan District, Guangzhou. CCT was measured using ultrasound pachymetry, and IOP using Tono-Pen applanation tonometer. The data were presented only for normal subjects.
Results: :
The mean IOP was 15.18±3.04mmHg, 15.06±3.06mmHg in right and left eyes, respectively. CCT was 541.34±32.69µm,542.35±31.24µm in right and left eyes, respectively. Negative correlation with age was observed for both IOP (r=-0.077, P=0.006 in right eyes; r=-0.065, P=0.020 in left eyes) and CCT (r=-0.129, P=0.000 in right eyes; r=-0.121, P=0.000 in left eyes). However, there was positive correlation with CCT and IOP(r=0.225, P=0.000 in right eyes; r=0.216, P=0.000 in left eyes). The IOP increased by 1.9mmHg for every 100µm increase of CCT in right eyes. This value was 2.0mmHg/100µm. IOP measurement deviated by 1.03 mmHg and 1.08 mmHg as per 10% CCT change in right and left eyes.
Conclusions: :
Older people appear to have a lower IOP and thinner CCT. IOP measurement was highly associated with CCT.
Keywords: intraocular pressure • clinical (human) or epidemiologic studies: risk factor assessment • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)