May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
The Relationship Between Central Corneal Thickness and Intraocular Pressure in Normal Subjects: The Liwan Eye Study
Author Affiliations & Notes
  • W. Huang
    Preventive Ophthalmology, Zhongshan Ophthalmic Center,, Guangzhou, China
  • Z. Yan-fa
    Preventive Ophthalmology, Zhongshan Ophthalmic Center,, Guangzhou, China
  • Q. Xia
    Preventive Ophthalmology, Zhongshan Ophthalmic Center,, Guangzhou, China
  • M. He
    Preventive Ophthalmology, Zhongshan Ophthalmic Center,, Guangzhou, China
  • Footnotes
    Commercial Relationships  W. Huang, None; Z. Yan-fa , None; Q. Xia , None; M. He, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 693. doi:https://doi.org/
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      W. Huang, Z. Yan-fa, Q. Xia, M. He; The Relationship Between Central Corneal Thickness and Intraocular Pressure in Normal Subjects: The Liwan Eye Study. Invest. Ophthalmol. Vis. Sci. 2008;49(13):693. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To assess the effects of central corneal thickness (CCT) on intraocular pressure (IOP) measurement, and the associations with age and gender.

Methods: : Adults aged 50 years and over were selected using cluster random sampling in Liwan District, Guangzhou. CCT was measured using ultrasound pachymetry, and IOP using Tono-Pen applanation tonometer. The data were presented only for normal subjects.

Results: : The mean IOP was 15.18±3.04mmHg, 15.06±3.06mmHg in right and left eyes, respectively. CCT was 541.34±32.69µm,542.35±31.24µm in right and left eyes, respectively. Negative correlation with age was observed for both IOP (r=-0.077, P=0.006 in right eyes; r=-0.065, P=0.020 in left eyes) and CCT (r=-0.129, P=0.000 in right eyes; r=-0.121, P=0.000 in left eyes). However, there was positive correlation with CCT and IOP(r=0.225, P=0.000 in right eyes; r=0.216, P=0.000 in left eyes). The IOP increased by 1.9mmHg for every 100µm increase of CCT in right eyes. This value was 2.0mmHg/100µm. IOP measurement deviated by 1.03 mmHg and 1.08 mmHg as per 10% CCT change in right and left eyes.

Conclusions: : Older people appear to have a lower IOP and thinner CCT. IOP measurement was highly associated with CCT.

Keywords: intraocular pressure • clinical (human) or epidemiologic studies: risk factor assessment • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) 
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