May 2008
Volume 49, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2008
In vivo Confocal Microscopy in Superior Limbic Keratoconjunctivitis
Author Affiliations & Notes
  • S. Doan
    Ophthalmology, Bichat Hospital, Paris, France
    Fondation A de Rothschild, Paris, France
  • A. Labbe
    Ophthalmology, Service 3, Quinze-Vingt Hospital, Paris, France
  • E. E. Gabison
    Ophthalmology, Bichat Hospital, Paris, France
    Fondation A de Rothschild, Paris, France
  • T. Hoang-Xuan
    Ophthalmology, Bichat Hospital, Paris, France
  • C. Baudouin
    Ophthalmology, Service 3, Quinze-Vingt Hospital, Paris, France
  • Footnotes
    Commercial Relationships  S. Doan, None; A. Labbe, None; E.E. Gabison, None; T. Hoang-Xuan, None; C. Baudouin, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2008, Vol.49, 804. doi:
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    • Get Citation

      S. Doan, A. Labbe, E. E. Gabison, T. Hoang-Xuan, C. Baudouin; In vivo Confocal Microscopy in Superior Limbic Keratoconjunctivitis. Invest. Ophthalmol. Vis. Sci. 2008;49(13):804.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To describe in vivo confocal microscopy findings in patients with superior limbic keratitis (SLK).

Methods: : Heidelberg HRT2 confocal microscopy examination of cornea and bulbar and palpebral conjunctiva was performed in 7 SLK patients (14 eyes). Three eyes had already undergone superior conjunctival resection.

Results: : The remarkable finding in all eyes was foci of conjunctivalization of the superior paralimbal cornea, with major desquamation and "snake like chromatin" pattern at the level of the superior bulbar conjunctival epithelium. No inflammatory cells were observed at this level, whereas superior palpebral conjunctiva was always infiltrated with round inflammatory cells.

Conclusions: : In vivo confocal microscopy in SLK patients findings are consistent with those reported by histological studies. This technique may be useful for the in vivo diagnostic of SLK.

Keywords: conjunctivitis • inflammation • imaging/image analysis: clinical 
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