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D. R. Williams, S. Sharma, M. Taban, P. K. Kaiser; Comparison of Retinal Thickness Measurements Using Automated Fast Macular Thickness Map versus 6 Radial Line Scans and Manual Measurement in Patients With Exudative AMD. Invest. Ophthalmol. Vis. Sci. 2008;49(13):905. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To compare automated retinal thickness values generated by the Stratus fast macular thickness maps (FMTM) and customized, high resolution 6-radial line scans versus manual retinal thickness measurements using the Stratus optical coherence tomography (OCT) scanner in patients with choroidal neovascularization (CNV) due to age-related macular degeneration (AMD).
Patients with wet AMD were imaged using the FMTM and 6-radial line scans on the Stratus OCT III (Carl Zeiss Meditec). Each scan was evaluated for errors in retinal segmentation at the fovea defined as the central 1-mm of the scan. Central retinal thickness measurements were determined manually from both the FMTM and radial line scans. Automated retinal thickness measurements of the foveal center point thickness, central subfield, total macular volume, signal strength, and software determination of low analysis confidence were also recorded for each type of scan. The presence/absence of epiretinal phenomenon, CNV, cystoid spaces, pigment epithelial detachment, and subretinal fluid was noted.
A total of 72 eyes (72 patients) were evaluated. 70% of FMTM scans and 88% of radial line scans were found to have >4 (out of 6) correct retinal boundaries at the fovea. 38% and 60% of automated foveal center point thickness on FMTM and radial line scans, respectively, lay within +/- 25 microns of the manual central retinal thickness. Comparing FMTM and radial line scans, 66% and 84% of automated foveal center point thickness and central subfield, respectively, were found to lay within +/- 25 microns of each other.
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