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S. Modjtahedi, B. Modjtahedi, L. S. Morse, D. G. Telander, S. S. Park; Comparison of Central Macular Thickness Between Stratus and Fourier-Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2008;49(13):919.
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To compare the central macular thickness measurements between Stratus optical coherence tomography (OCT) and commercially available Fourier-domain optical coherence tomography (Fd-OCT, Optovue).
Retrospective chart review of all patients seen between January to July 2007 who had both Stratus and Fd-OCT imaging of the macula done on the same day.
Records of 138 eyes from 111 subjects were reviewed. The most common pathologies included choroidal neovascular membrane (33%), epiretinal membrane (21%), and cystoid macular edema (9%). Twenty eight eyes (20%) were normal. The mean central macular thickness was 290 + 124 microns (range 125-768 microns) with Stratus OCT versus 310 + 124 microns (range 83-784 microns) with Fd-OCT . The difference in central macular thickness ranged from 1 to 130 microns. The absolute mean paired difference between the two machines was 19.6 + 3.0 microns (p < 0.01); only 14 eyes (10%) had a difference > 60 microns.
Although a statistically significant difference in central macular thickness was noted between Stratus and Fd-OCT, this difference was small in most cases.
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