Comparison of Central Macular Thickness Between Stratus and Fourier-Domain Optical Coherence Tomography

Abstract

Purpose: : To compare the central macular thickness measurements between Stratus optical coherence tomography (OCT) and commercially available Fourier-domain optical coherence tomography (Fd-OCT, Optovue).

Methods: : Retrospective chart review of all patients seen between January to July 2007 who had both Stratus and Fd-OCT imaging of the macula done on the same day.

Results: : Records of 138 eyes from 111 subjects were reviewed. The most common pathologies included choroidal neovascular membrane (33%), epiretinal membrane (21%), and cystoid macular edema (9%). Twenty eight eyes (20%) were normal. The mean central macular thickness was 290 + 124 microns (range 125-768 microns) with Stratus OCT versus 310 + 124 microns (range 83-784 microns) with Fd-OCT . The difference in central macular thickness ranged from 1 to 130 microns. The absolute mean paired difference between the two machines was 19.6 + 3.0 microns (p < 0.01); only 14 eyes (10%) had a difference > 60 microns.

Conclusions: : Although a statistically significant difference in central macular thickness was noted between Stratus and Fd-OCT, this difference was small in most cases.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical • retina