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S. Pedenovi, C. M. Eandi, F. Bottoni, G. Staurenghi; Spectral Domain Optical Coherence Tomography Evaluation of Idiopathic Juxtafoveal Retinal Telangectasia (Group 2A). Invest. Ophthalmol. Vis. Sci. 2008;49(13):927. doi: https://doi.org/.
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to describe the clinical features of idiopathic juxtafoveal retinal telangectasia (IJRT) group 2A examined with a spectral domain optical coherence tomography (OCT).
we reviewed the fluorescein angiography (FA), fundus autofluorescence (FAF) and OCT images of 12 eyes of 6 patients affected by IJRT group 2A. FA,FAF and OCT images were simultaneously obtained with a combined instrument for confocal scanning laser ophthalmoscopy (SLO) and spectral domain OCT (HRA-OCT Spectralis, axial resolution of 7 µm. Heidelberg Engineering, Heidelberg, Germany). In 1 patient FA was not performed.
There were four male and two female patients. Mean age was 60,6 years (range 42-77 years). One patient presented bilateral IJRT 2A with associated subfoveal choroidal neovascolarization. Therefore he was excluded from our analysis. All FAF images showed the absence of the masking macular pigment in the fovea. In case 1,2,4 bilaterally and 6 monolaterally, an even increased foveal autofluorescence (AF) was detected. Spectral domain OCT images showed a perfect correlation between this increased foveal AF and an intraretinal cyst. Whenever a foveal cyst was recorded (case 1,2,4,6), the OCT image also highlighted an interruption of the outer plexiform layer (OPL) at the edges of the cyst.All FA images revealed a late leakage in the area corresponding to IJRT. Noteworthy, the corresponding OCT scans did not confirm the presence of intraretinal fluid and/or cysts .In both eyes of cases 1 and 2, and in the right eye of case 4 OCT revealed an increased thickness of the inner nuclear layer, inner plexiform layer and ganglion cell layer in the juxtafoveal temporal area. This area corresponded to the most leaky areas in FA.
1. The increased foveal AF is caused by absence of OPL corresponding to the intraretinal cyst.2. There is an absence of intraretinal liquid or cysts in the areas of fluorangiographic leakage3. Thickening of inner retinal layers in the area corresponding to the most leaky areas in FA is a frequent findings.
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