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C. Huot, K. B. Desai; Spectral Domain Optical Coherence Tomography Characteristics of Combined Hamartoma of the Retina and Retinal Pigment Epithelium. Invest. Ophthalmol. Vis. Sci. 2008;49(13):932. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To report the spectral domain optical coherence tomography (OCT)findings of two patients with combined hamartoma of the retinaand retinal pigment epithelium (RPE).
Retinal imaging was obtained utilizing spectral domain OCT.
Case 1: Spectral domain OCT displays a preretinal membrane,retinal disorganization, and thickened retina drawn into folds.Vitreoretinal interface changes and pigmentation are presentin the posterior pole on fundus photography. Fluorescein angiographydemonstrates hyperfluorescence in the late phase.
Case 2: Spectral domain OCT shows edema andouter retinal thickening and hyperreflectivity associated withthe combined hamartoma of the retina and RPE. Neighboring areasof retina demonstrate relatively preserved microarchitecture.Fundus photography shows a pigmented lesion that shows latehyperfluorescence on fluorescein angiography.
Spectral domain OCT provides higher resolution and faster acquisitiontimes than conventional time domain OCT by utilizing Fourier-domaintechnology. This allows generation of 3-dimensional imagingwith orthogonal cross-sectional images displayed within the3D image. Its higher resolution allows more detailed observationof the vitreoretinal interface abnormalities and retinal disorganizationpresent in combined hamartomas of the retina and RPE and aidsin the differential diagnosis of pigmented fundus lesions.
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