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R. E. Fintelmann, B. D. Ayres, J. I. Maguire, A. C. Ho, H. F. Chew; Characteristics of Endophthalmitis in Patients With the Boston Keratoprostheses. Invest. Ophthalmol. Vis. Sci. 2008;49(13):953.
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What are the characteristics of endophthalmitis in patients with the Boston Keratoprostheses?
Chart review of 4 out of 35 patients who underwentKeratoprosthesis implantation on the Wills Eye Cornea service from 2001-2007 and who developed endophthalmitis.
All four patients underwent surgery because of failed graft. The incidence of endophthalmitis was 11.4%. All of them occurred late (5-57 months). Three of the four patients had been on topical Vancomycin drops. All four patients underwent a tap and inject and were treated as inpatients for three to seven days with intensive topical and systemic therapy. Three out of four had culture positive results: Two coagulase negative Staphylococcus, one Pseudomonas and Staphycoloccus aureus.
Endophthalmitis can occur after Boston Keratoprostheses at a significant rate even in low risk patients on prophylactic vancomycin drops.
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